Material processing of hydroxyapatite and titanium alloy (HA/Ti) composite as implant materials using powder metallurgy: A review

被引:283
作者
Arifin, Amir [1 ,2 ]
Sulong, Abu Bakar [1 ]
Muhamad, Norhamidi [1 ]
Syarif, Junaidi [1 ]
Ramli, Mohd Ikram [1 ]
机构
[1] Univ Kebangsaan Malaysia, Dept Mech & Mat Engn, Bangi 43600, Selangor, Malaysia
[2] Sriwijaya Univ, Dept Mech Engn, Indralaya, Sumatera Selata, Indonesia
关键词
Ceramic-metal composite; Powder metallurgy; Material processing; Biocompatibility; Mechanical properties; IN-VITRO BIOACTIVITY; MECHANICAL-PROPERTIES; POROUS HYDROXYAPATITE; TI/HA COMPOSITES; NITI ALLOY; FABRICATION; COATINGS; TI; TEMPERATURE; PARAMETERS;
D O I
10.1016/j.matdes.2013.09.045
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The bio-active and biodegradable properties of hydroxyapatite (HA) make this material a preferred candidate for implants such as bone replacement in replacing natural tissues damaged by diseases and accidents. However, the low mechanical strength of HA hinders its application. Combining HA with a biocompatible material with a higher mechanical strength, such as a titanium (Ti) alloy, to form a composite has been of interest to researchers. A HA/Ti composite would possess characteristics essential to modern implant materials, such as bio-inertness, a low Young's modulus, and high biocompatibility. However, there are issues in the material processing, such as the rheological behavior, stress-shielding, diffusion mechanism and compatibility between the two phases. This paper reviews the HA and Ti alloy interactions under various conditions, in vitro and in vivo tests for HA/Ti composites, and common powder metallurgy processes for HA/Ti composites (e. g., pressing and sintering, isostatic pressing, plasma spraying, and metal injection molding). (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:165 / 175
页数:11
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