Differentiated Thyroid Cancer in childhood

被引：3

作者：

Leboulleux, Sophie ^{[1
]}

Hartl, Dana ^{[2
]}

Baudin, Eric ^{[1
]}

Schlumberger, Martin ^{[1
]}

机构：

[1] Univ Paris 11, Inst Gustave Roussy, Serv Med Nucl & Cancerol Endocrinienne, F-94805 Villejuif, France

[2] Inst Gustave Roussy, Serv Chirurg, F-94805 Villejuif, France

来源：

BULLETIN DU CANCER | 2012年 / 99卷 / 11期

关键词：

differentiated thyroid cancer; childhood; diagnosis; prognosis; treatment; SUBSEQUENT MALIGNANT NEOPLASMS; CHILDREN; CARCINOMA; RADIATION; ADOLESCENTS; RISK; LOCALIZATION; RECURRENCE; MANAGEMENT; MUTATIONS;

D O I：

10.1684/bdc.2012.1645

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Thyroid carcinoma is a rare disease in children, and is mostly of the papillary histological type. Lymph node metastases are frequent at diagnosis, being present in 23 to 74% of the cases and can reveal the cancer in about one fourth of cases. Lung metastases are present at initial diagnosis in 6 to 20% of cases. The main known risk factor for thyroid cancer is a previous history of radiation exposure. Treatment includes surgery with total thyroidectomy and lymph node dissection and radioiodine therapy in case of extensive disease and distant metastases. Life-long thyroxine treatment is given to all patients. Long term prognosis is favourable, but thyroid cancer related deaths have been reported some decades after initial treatment.

引用

页码：1093 / 1099

页数：7

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