Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature

被引:4
作者
Ren, Weigang [1 ]
Zhong, Zhaohui [1 ]
Zhao, Xiaokun [1 ]
Yang, Junjie [2 ]
Zhang, Lei [1 ]
Xu, Ran [1 ]
Li, Songchao [1 ]
Zhu, Xuan [1 ]
Lu, Chen [3 ]
Chin, Joseph L. [4 ]
机构
[1] Cent S Univ, Xiangya Hosp 2, Dept Urol, Changsha 410011, Hunan, Peoples R China
[2] Cent S Univ, Xiangya Hosp 2, Dept Hematol, Changsha 410011, Hunan, Peoples R China
[3] Shanghai Changhai Hosp, Dept Urol, Shanghai 200433, Peoples R China
[4] Univ Western Ontario, Dept Urol & Oncol, London, ON N6A 4V2, Canada
关键词
primary testicular non-Hodgkin's lymphoma; hemophagocytic syndrome; testicular natural killer/T-cell lymphoma; hemophagocytosis; T-CELL LYMPHOMA; MALIGNANT-LYMPHOMA; CLINICAL-FEATURES; TESTIS; LYMPHOHISTIOCYTOSIS;
D O I
10.3892/ol.2012.701
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary testicular non-Hodgkin's lymphoma (TNHL) was first described as a clinical entity in 1866. It is a rare disease which accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. Hemophagocytic syndrome (UPS) is a rare but distinct condition caused by inappropriate and dysregulated activation of the immune system. We report a 47-year-old man with primary TNHL who developed HPS four months after occurrence of scrotal swelling. To the best of our knowledge, primary TNHL associated with HPS has not previously been reported.
引用
收藏
页码:59 / 62
页数:4
相关论文
共 21 条
[1]   A 31-year-old man with bilateral testicular enlargement - Precursor B-cell lymphoblastic lymphoma. [J].
Ballen, KK ;
Hasserjian, RP .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (20) :2081-2087
[2]   PRIMARY LYMPHOMA OF THE TESTIS [J].
BUSKIRK, SJ ;
EVANS, RG ;
BANKS, PM ;
OCONNELL, MJ ;
EARLE, JD .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1982, 8 (10) :1699-1703
[3]   Nonnasal lymphoma expressing the natural killer cell marker CD56: A clinicopathologic study of 49 cases of an uncommon aggressive neoplasm [J].
Chan, JKC ;
Sin, VC ;
Wong, KF ;
Ng, CS ;
Tsang, WYW ;
Chan, CH ;
Cheung, MMC ;
Lau, WH .
BLOOD, 1997, 89 (12) :4501-4513
[4]   Primary non-Hodgkin's lymphoma of the nose and nasopharynx: Clinical features, tumor immunophenotype, and treatment outcome in 113 patients [J].
Cheung, MMC ;
Chan, JKC ;
Lau, WH ;
Foo, W ;
Chan, PTM ;
Ng, CS ;
Ngan, RKC .
JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (01) :70-77
[5]   Epstein-Barr virus (EBV) latent membrane protein-1 down-regulates tumor necrosis factor-α (TNF-α) receptor-1 and confers resistance to TNF-α-induced apoptosis in T cells -: Implication for the progression to T-cell lymphoma in EBV-associated hemophagocytic syndrome [J].
Chuang, Huai-Chia ;
Lay, Jong-Ding ;
Chuang, Shuang-En ;
Hsieh, Wen-Chuan ;
Chang, Yao ;
Su, Ih-Jen .
AMERICAN JOURNAL OF PATHOLOGY, 2007, 170 (05) :1607-1617
[6]   Malignant lymphoma of the testis [J].
Eskey, CJ ;
Whitman, GJ ;
Chew, FS .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1997, 169 (03) :822-822
[7]  
FALINI B, 1990, BLOOD, V75, P434
[8]   Human herpesvirus 8-associated hemophagocytic lymphohistiocytosis in human immunodeficiency virus-infected patients [J].
Fardet, L ;
Blum, L ;
Kerob, D ;
Agbalika, F ;
Galicier, L ;
Dupuy, A ;
Lafaurie, M ;
Meignin, V ;
Morel, P ;
Lebbé, C .
CLINICAL INFECTIOUS DISEASES, 2003, 37 (02) :285-291
[9]   Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome [J].
Han, A-Reum ;
Lee, Hye Ran ;
Park, Byeong-Bae ;
Hwang, In Gyu ;
Park, Sarah ;
Lee, Sang Cheol ;
Kim, Kihyun ;
Lim, Ho Yeong ;
Ko, Young H. ;
Kim, Sun Hee ;
Kim, Won Seog .
ANNALS OF HEMATOLOGY, 2007, 86 (07) :493-498
[10]   Familial and acquired hemophagocytic lymphohistiocytosis [J].
Janka, Gritta E. .
EUROPEAN JOURNAL OF PEDIATRICS, 2007, 166 (02) :95-109