Histamine 4 Receptor Antagonism modulates TH2 cell function, IL13 production, and lung remodeling in a model of chronic asthma

被引：0
|
作者：
Cowden, Jeffery [1 ]
Riley, Jason [1 ]
Thurmond, Robin [1 ]
Dunford, Paul J. [1 ]
机构：
[1] Johnson Johnson PRD, Immunol, San Diego, CA USA
来源：
FASEB JOURNAL | 2008年 / 22卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [1] ELEVATED EXPRESSION OF THE TH2 CYTOKINES IL-4 AND IL-13 IN A SHEEP MODEL OF ALLERGIC ASTHMA
    Liravi, B. K.
    Piedrafita, D.
    Bischof, R. J.
    RESPIROLOGY, 2012, 17 : 51 - 51
  • [2] Stimulation of the histamine 4 receptor with 4-methylhistamine modulates the effects of chronic stress on the Th1/Th2 cytokine balance
    Ahmad, Sheikh Fayaz
    Zoheir, Khairy M. A.
    Ansari, Mushtaq Ahrnad
    Korashy, Hesharn M.
    Bakheet, Saleh A.
    Ashour, Abdelkader E.
    Attia, Sabry M.
    IMMUNOBIOLOGY, 2015, 220 (03) : 341 - 349
  • [3] Sputum Expression Of Il-13rα2 Correlates With Airway Remodeling And Th2 Inflammation In Asthma
    Nezgovorova, V.
    Liu, Q.
    Niu, N.
    Holm, C.
    Grant, N. P.
    Marone, S.
    Ravage-Mass, L.
    Lee, C.
    Elias, J. A.
    Cohn, L.
    Chupp, G. L.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
  • [4] Histamine 4 receptor (H4R) antagonism reduces edema in a Th2 and IgE dependent model of atopic dermatitis
    Cowden, J. M.
    Zhang, M.
    Thurmond, R. L.
    Dunford, P. J.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (01) : S239 - S239
  • [5] Th2 cell responses are mediated by the histamine H4 receptor
    Thurmond, Robin L.
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, 106 : 20P - 20P
  • [6] EFFECTS OF TH2 CYTOKINES IL-4 AND IL-13 ON LYMPHATIC VESSELS IN THE LUNG
    Sin, K. H.
    Rpkataru
    Lee, S. H.
    RESPIROLOGY, 2013, 18 : 20 - 20
  • [7] Comparative roles of IL-4, IL-13, and IL-4Rα in dendritic cell maturation and CD4+ Th2 cell function
    Webb, Dianne C.
    Cai, Yeping
    Matthaei, Klaus I.
    Foster, Paul S.
    JOURNAL OF IMMUNOLOGY, 2007, 178 (01): : 219 - 227
  • [8] Asthma-associated IL13 single nucleotide polymorphisms (SNPs) upregulate human IL4 expression in mice carrying a human Th2 locus BAC transgene
    Pivniouk, Vadim
    Bailey, Tom
    Pivniouk, Oksana
    Rosenbaum, David
    Mobley, Sara
    Stern, Debra
    Halonen, Marilyn
    Vercelli, Donata
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [9] IL-4 and IL13 promote liver fibrosis signaling through M2 macrophages, but not Th2 T cells or hepatocytes
    Weng, S-Y
    Wang, X.
    Vijayan, S.
    Kim, Y. O.
    Kaps, L.
    Tang, Y.
    Molokanova, O.
    Crosby, J.
    Mccaleb, M.
    Brombacher, F.
    Waisman, A.
    Bockamp, E.
    Schuppan, D.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S655 - S655
  • [10] Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammation
    Cameron, Lisa
    Webster, Robin B.
    Strempel, Jannine M.
    Kiesler, Patricia
    Kabesch, Michael
    Ramachandran, Harikrishnan
    Yu, Lizhi
    Stern, Debra A.
    Graves, Penelope E.
    Lohman, I. Carla
    Wright, Anne L.
    Halonen, Marilyn
    Klimecki, Walter T.
    Vercelli, Donata
    JOURNAL OF IMMUNOLOGY, 2006, 177 (12): : 8633 - 8642
12345