Quinoxaline: An insight into the recent pharmacological advances

被引：167

作者：

Tariq, Sana ^{[1
]}

Somakala, K. ^{[1
]}

Amir, Mohd. ^{[1
]}

机构：

[1] Hamdard Univ, Sch Pharmaceut Educ & Res, Dept Pharmaceut Chem, New Delhi 110062, India

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2018年 / 143卷

关键词：

Quinoxaline; Biological applications; Anti-cancer; Antimalarial; Anti-inflammatory; Antimicrobial; VITRO ANTIBACTERIAL ACTIVITY; ANTI-HIV ACTIVITY; BIOLOGICAL EVALUATION; 1,4-DI-N-OXIDE DERIVATIVES; ANTIINFLAMMATORY AGENTS; ANTIMICROBIAL ACTIVITY; SULFONAMIDO-QUINOXALINES; RECEPTOR ANTAGONISTS; ANTIMALARIAL AGENTS; ANALGESIC AGENTS;

D O I：

10.1016/j.ejmech.2017.11.064

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Quinoxaline, a fused heterocycle of benzene and pyrazine rings has gained considerable attention in the field of contemporary medicinal chemistry. The moiety is of substantial importance because of its wide array of pharmacological activities viz. anti-cancer, antimalarial, anti-inflammatory, antimicrobial, anti HIV etc. Diversely substituted quinoxalines are important therapeutic agents in the pharmaceutical industry. This review focusses on the quinoxaline derivatives developed during the last decennial period and their biomedical applications. A compilation of patents on quinoxaline is also included herein. (C) 2017 Elsevier Masson SAS. All rights reserved.

引用

页码：542 / 557

页数：16

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