Concordance of Resistance Profiles in Households of Patients With Multidrug-Resistant Tuberculosis

被引:15
作者
Parr, Jonathan B. [1 ,2 ,3 ]
Mitnick, Carole D. [1 ,2 ,3 ]
Atwood, Sidney S. [1 ]
Chalco, Katiuska [3 ]
Bayona, Jaime [3 ]
Becerra, Mercedes C. [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Div Global Hlth Equ, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Global Hlth & Social Med, Boston, MA 02115 USA
[3] Partners In Hlth, Boston, MA USA
基金
比尔及梅琳达.盖茨基金会;
关键词
DST; discordant; presumptive; empirical; contact; MYCOBACTERIUM-TUBERCULOSIS; REGIMENS;
D O I
10.1093/cid/cit709
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We estimated the proportion of household contacts whose drug-susceptibility test results matched those of the purported source patient with multidrug-resistant tuberculosis. Ninety-nine (88.4%) contacts had isolates resistant to isoniazid and rifampin, and 41 (36.6%) contacts had isolates with results that also matched the purported source for ethambutol, streptomycin, and pyrazinamide.
引用
收藏
页码:392 / 395
页数:4
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