Sodium hydride-mediated synthesis of 1,5-diaryl-1,2,3-triazoles from anti-3-aryl-2,3-dibromopropanoic acids and organic azides

被引：4

作者：

Cheng, Xue-Zhi ^{[1
]}

Liu, Wei ^{[1
]}

Huang, Zhen-Dong ^{[2
]}

Kuang, Chun-Xiang ^{[1
,3
]}

机构：

[1] Tongji Univ, Dept Chem, Shanghai 200092, Peoples R China

[2] Zhejiang Citrus Res Inst, Taizhou 318020, Peoples R China

[3] Minist Educ, Key Lab Yangtze River Water Environm, Shanghai 200092, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2013年 / 24卷 / 08期

关键词：

Cyclizations; Heterocycles; Sodium hydride; Triazoles; CYCLOADDITION;

D O I：

10.1016/j.cclet.2013.05.007

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of 1,5-disubstituted 1,2,3-triazoles are synthesized by a one-pot process from anti-3-aryl-2,3-dibromopropanoic acids and organic azides mediated by sodium hydride in dimethyl sulfoxide. The reaction is mild and simple, does not require a transition-metal catalyst, and gives products in good to excellent yields. (C) 2013 Chun-Xiang Kuang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

引用

页码：764 / 766

页数：3

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