Synergistic Photoredox Catalysis and Organocatalysis for Inverse Hydroboration of Imines

被引：141
作者：
Zhou, Nengneng [1 ]
Yuan, Xiang-Ai [2 ]
Zhao, Yue [1 ]
Xie, Jin [1 ]
Zhu, Chengjian [1 ,3 ]
机构：
[1] Nanjing Univ, State Key Lab Coordinat Chem, Jiangsu Key Lab Adv Organ Mat, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China
[2] Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Peoples R China
[3] Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 15期
基金：
中国国家自然科学基金;
关键词：
C-B coupling; hydroboration; imines; photochemistry; radicals; HETEROCYCLIC CARBENE-BORANES; C-H BONDS; AMINO BORONATE ESTERS; VISIBLE-LIGHT; RADICAL REACTIONS; BORYL RADICALS; PINACOLBORYL ADDITION; CARBONYL DERIVATIVES; ASYMMETRIC-SYNTHESIS; ORGANIC-SYNTHESIS;
D O I：
10.1002/anie.201800421
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first catalytic inverse hydroboration of imines with N-heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis. This catalytic combination provides a promising platform for promoting NHC-boryl radical chemistry under sustainable and radical-initiator-free conditions. The highly important functional-group compatibility and possible application in late-stage hydroborations represent an important step forward to an enhanced alpha-amino organoboron library.
引用
收藏
页码：3990 / 3994
页数：5
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