Synergistic Photoredox Catalysis and Organocatalysis for Inverse Hydroboration of Imines

被引：141

作者：

Zhou, Nengneng ^{[1
]}

Yuan, Xiang-Ai ^{[2
]}

Zhao, Yue ^{[1
]}

Xie, Jin ^{[1
]}

Zhu, Chengjian ^{[1
,3
]}

机构：

[1] Nanjing Univ, State Key Lab Coordinat Chem, Jiangsu Key Lab Adv Organ Mat, Sch Chem & Chem Engn, Nanjing 210023, Jiangsu, Peoples R China

[2] Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Peoples R China

[3] Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2018年 / 57卷 / 15期

基金：

中国国家自然科学基金;

关键词：

C-B coupling; hydroboration; imines; photochemistry; radicals; HETEROCYCLIC CARBENE-BORANES; C-H BONDS; AMINO BORONATE ESTERS; VISIBLE-LIGHT; RADICAL REACTIONS; BORYL RADICALS; PINACOLBORYL ADDITION; CARBONYL DERIVATIVES; ASYMMETRIC-SYNTHESIS; ORGANIC-SYNTHESIS;

D O I：

10.1002/anie.201800421

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first catalytic inverse hydroboration of imines with N-heterocyclic carbene (NHC) boranes has been realized by means of cooperative organocatalysis and photocatalysis. This catalytic combination provides a promising platform for promoting NHC-boryl radical chemistry under sustainable and radical-initiator-free conditions. The highly important functional-group compatibility and possible application in late-stage hydroborations represent an important step forward to an enhanced alpha-amino organoboron library.

引用

页码：3990 / 3994

页数：5

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