Synthesis of an 11C-Labeled Antiprion GN8 Derivative and Evaluation of Its Brain Uptake by Positron Emission Tomography

被引：7
|
作者：
Kimura, Tsutomu [1 ]
Sako, Takeo [2 ]
Siqin [2 ]
Hosokawa-Muto, Junji [1 ]
Cui, Yi Long [2 ]
Wada, Yasuhiro [2 ]
Kataoka, Yosky [2 ]
Doi, Hisashi [2 ]
Sakaguchi, Suehiro [3 ]
Suzuki, Masaaki [2 ]
Watanabe, Yasuyoshi [2 ]
Kuwata, Kazuo [1 ]
机构：
[1] Gifu Univ, United Grad Sch Drug Discovery & Med Informat Sci, Ctr Emerging Infect Dis, Gifu 5011194, Japan
[2] RIKEN Ctr Mol Imaging Sci, Chuo Ku, Kobe, Hyogo 6500047, Japan
[3] Univ Tokushima, Inst Enzyme Res, Tokushima 7708503, Japan
来源：
CHEMMEDCHEM | 2013年 / 8卷 / 07期
关键词：
antiprion agents; brain uptake; positron emission tomography (PET); prion diseases; radiolabeling; TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES; CREUTZFELDT-JAKOB-DISEASE; PRION PROTEIN; PROSTACYCLIN RECEPTOR; SURVIVAL-TIME; QUINACRINE; PET; INFECTION; COMPOUND; INFUSION;
D O I：
10.1002/cmdc.201300167
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：1035 / 1039
页数：5
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