Equilibrium and sensitivity analysis of a spatio-temporal host-vector epidemic model

被引:6
作者
Martin, Olivier [1 ]
Fernandez-Diclo, Yasmil [1 ]
Coville, Jerome [1 ]
Soubeyrand, Samuel [1 ]
机构
[1] INRAE, BioSP, F-84914 Avignon, France
基金
欧盟地平线“2020”;
关键词
Equilibrium analysis; Compartmental model; Global sensitivity analysis; Partial differential equations; Transient phase; Xylella fastidiosa; DIFFUSION;
D O I
10.1016/j.nonrwa.2020.103194
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Insect-borne diseases are diseases carried by insects affecting humans, animals or plants. They have the potential to generate massive outbreaks such as the Zika epidemic in 2015-2016 mostly distributed in the Americas, the Pacific and Southeast Asia, and the multi-foci outbreak caused by the bacterium Xylella fastidiosa in Europe in the 2010s. In this article, we propose and analyze the behavior of a spatially-explicit compartmental model adapted to pathosystems with fixed hosts and mobile vectors disseminating the disease. The behavior of this model based on a system of partial differential equations is complementarily characterized via a theoretical study of its equilibrium states and a numerical study of its transient phase using global sensitivity analysis. The results are discussed in terms of implications concerning the surveillance and control of the disease over a medium-to-long temporal horizon. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页数:19
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