Comparing the clinical profile of non obese children with sleep apnea and snoring

被引:1
作者
Soares Stefanini, Daniele de Oliveira [1 ]
de Barros, Emilia Leite [1 ]
Stefanini, Renato [1 ]
de Cassia Pradella-Hallinan, Marcia Lurdes [1 ]
Nagata Pignatari, Shirley Shizue [1 ]
Fujita, Reginaldo Raimundo [1 ]
机构
[1] Univ Fed Sao Paulo, Sao Paulo, Brazil
关键词
child; metabolic diseases; polysomnography; sleep apnea; obstructive; METABOLIC SYNDROME; BLOOD-PRESSURE; INSULIN; INFLAMMATION;
D O I
暂无
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Few studies in the literature have looked into the cardiovascular and metabolic effects of Obstructive Sleep Apnea Syndrome (OSAS) in children. Objective: This study aims to evaluate the metabolic profile of non-obese children with OSAS. Methods: Fifty-two children were enrolled in this study, 21 girls and 31 boys. Patients were divided into two groups: OSAS (28 children) and Snore (22 children) according to polysomnographic evaluation. All children were submitted to ENT examination, measurements of weight, height and blood pressure. Blood samples were tested for hemoglobin, hematocrit, fasting glucose, fasting insulin, triglycerides, total cholesterol, HDL, LDL, VLDL, TSH and T4. The gathered data sets were compared between groups and also within the OSAS group according to the severity of the syndrome. Results: The children from both groups had no alterations in blood pressure levels. The results of the blood tests were normal for both groups. Results of hemoglobin, hematocrit, and HDL were all significantly higher in the Snore group when compared to the OSAS group; by their turn, VLDL levels were higher in the OSAS group. There was no statistical difference between the groups based on OSAS severity. Conclusion: Non-obese children with OSAS present no significant alterations in metabolic tests or blood pressure levels.
引用
收藏
页码:22 / 26
页数:5
相关论文
共 26 条
  • [1] Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathing
    Amin, RS
    Carroll, JL
    Jeffries, JL
    Grone, C
    Bean, JA
    Chini, B
    Bokulic, R
    Daniels, SR
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 169 (08) : 950 - 956
  • [2] Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea
    Amin, RS
    Kimball, TR
    Bean, JA
    Jeffries, JL
    Willging, JP
    Cotton, RT
    Witt, SA
    Glascock, BJ
    Daniels, SR
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (10) : 1395 - 1399
  • [3] Left ventricular function in children with sleep-disordered breathing
    Amin, RS
    Kimball, TR
    Kalra, M
    Jeffries, JL
    Carroll, JL
    Bean, JA
    Witt, SA
    Glascock, BJ
    Daniels, SR
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2005, 95 (06) : 801 - 804
  • [4] A COMPARISON OF TONSILLAR SIZE AND OROPHARYNGEAL DIMENSIONS IN CHILDREN WITH OBSTRUCTIVE ADENOTONSILLAR HYPERTROPHY
    BRODSKY, L
    MOORE, L
    STANIEVICH, JF
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 1987, 13 (02) : 149 - 156
  • [5] Sleep-disordered breathing and cardiovascular risk
    Caples, Sean M.
    Garcia-Touchard, Arturo
    Somers, Virend K.
    [J]. SLEEP, 2007, 30 (03) : 291 - 303
  • [6] Metabolic correlates with obstructive sleep apnea in obese subjects
    de la Eva, RC
    Baur, LA
    Donaghue, KC
    Waters, KA
    [J]. JOURNAL OF PEDIATRICS, 2002, 140 (06) : 654 - 659
  • [7] Preoperative and postoperative cardiac and clinical findings of patients with adenotonsillar hypertrophy
    Görür, K
    Döven, O
    Ünal, M
    Akkus, N
    Özcan, C
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2001, 59 (01) : 41 - 46
  • [8] Inflammatory pathways and insulin action
    Hotamisligil, GS
    [J]. INTERNATIONAL JOURNAL OF OBESITY, 2003, 27 (Suppl 3) : S53 - S55
  • [9] Obstructive sleep-disordered breathing and fasting insulin levels in nonobese children
    Kaditis, AG
    Alexopoulos, EI
    Damani, E
    Karadonta, I
    Kostadima, E
    Tsolakidou, A
    Gourgoulianis, K
    Syrogiannopoulos, GA
    [J]. PEDIATRIC PULMONOLOGY, 2005, 40 (06) : 515 - 523
  • [10] Inflammatory aspects of sleep apnea and their cardiovascular consequences
    Kasasbeh, E.
    Chi, David S.
    Krishnaswamy, G.
    [J]. SOUTHERN MEDICAL JOURNAL, 2006, 99 (01) : 58 - 67