Metabolic engineering for advanced biofuels production from Escherichia coli

被引：217

作者：

Atsumi, Shota ^{[1
]}

Liao, James C. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2008年 / 19卷 / 05期

关键词：

D O I：

10.1016/j.copbio.2008.08.008

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Global energy and environmental problems have stimulated increasing efforts toward synthesizing liquid biofuels as transportation energy. Compared to the traditional biofuel, ethanol, advanced biofuels should offer advantages such as higher energy density, lower hygroscopicity, lower vapor pressure, and compatibility with existing transportation infrastructure. However, these fuels are not synthesized economically using native organisms. Metabolic engineering offers an alternative approach in which synthetic pathways are engineered into user-friendly hosts for the production of these fuel molecules. These hosts could be readily manipulated to improve the production efficiency. This review summarizes recent progress in the engineering of Escherichia coli to produce advanced biofuels.

引用

页码：414 / 419

页数：6

共 27 条

[11] PURIFICATION AND CHARACTERIZATION OF A PRIMARY-SECONDARY ALCOHOL-DEHYDROGENASE FROM 2 STRAINS OF CLOSTRIDIUM-BEIJERINCKII
ISMAIEL, AA
ZHU, CX
COLBY, GD
CHEN, JS
[J]. JOURNAL OF BACTERIOLOGY, 1993, 175 (16) : 5097 - 5105
[12] GENETIC AND MOLECULAR CHARACTERIZATION OF THE GENES INVOLVED IN SHORT-CHAIN FATTY-ACID DEGRADATION IN ESCHERICHIA-COLI - THE ATO SYSTEM
JENKINS, LS
NUNN, WD
[J]. JOURNAL OF BACTERIOLOGY, 1987, 169 (01) : 42 - 52
[13] ACETONE-BUTANOL FERMENTATION REVISITED
JONES, DT
WOODS, DR
[J]. MICROBIOLOGICAL REVIEWS, 1986, 50 (04) : 484 - 524
[14] Microdiesel:: Escherichia coli engineered for fuel production
Kalscheuer, Rainer
Stoelting, Torsten
Steinbuechel, Alexander
[J]. MICROBIOLOGY-SGM, 2006, 152 : 2529 - 2536
[15] BIOSYNTHESIS OF NORVALINE, NORLEUCINE, AND HOMOISOLEUCINE IN SERRATIA-MARCESCENS
KISUMI, M
SUGIURA, M
CHIBATA, I
[J]. JOURNAL OF BIOCHEMISTRY, 1976, 80 (02) : 333 - 339
[16] NOVEL NADP-LINKED ALCOHOL-ALDEHYDE-KETONE OXIDOREDUCTASE IN THERMOPHILIC ETHANOLOGENIC BACTERIA
LAMED, RJ
ZEIKUS, JG
[J]. BIOCHEMICAL JOURNAL, 1981, 195 (01) : 183 - 190
[17] LIN YL, 1983, APPL ENVIRON MICROB, V45, P966, DOI 10.1128/AEM.45.3.966-973.1983
[18] CONSTRUCTION OF L-THREONINE OVERPRODUCING STRAINS OF ESCHERICHIA-COLI K-12 USING RECOMBINANT DNA TECHNIQUES
MIWA, K
TSUCHIDA, T
KURAHASHI, O
NAKAMORI, S
SANO, K
MOMOSE, H
[J]. AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1983, 47 (10): : 2329 - 2334
[19] Cloning and analysis of the genes for a novel electron-transferring flavoprotein from Megasphaera elsdenii -: Expression and characterization of the recombinant protein
O'Neill, H
Mayhew, SG
Butler, G
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (33) : 21015 - 21024
[20] Osburn OL, 1937, J BIOL CHEM, V121, P685

← 1 2 3 →