Antimicrobial and antioxidant activity of the essential oil from the Carpathian Thymus alternans Klokov

被引:13
作者
Vitali, Luca A. [1 ]
Dall'Acqua, Stefano [2 ]
Maggi, Filippo [1 ]
Martonfi, Pavol [3 ]
Papa, Fabrizio [4 ]
Petrelli, Dezemona [5 ]
Sut, Stefania [2 ]
Lupidi, Giulio [1 ]
机构
[1] Univ Camerino, Sch Pharm, Camerino, Italy
[2] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Padua, Italy
[3] Safarik Univ, Inst Biol & Ecol, Dept Bot, Kosice, Slovakia
[4] Univ Camerino, Sch Sci & Technol, Camerino, Italy
[5] Univ Camerino, Sch Biosci & Vet Med, Camerino, Italy
关键词
Thymus alternans; essential oil; (E)-nerolidol; antimicrobial; antioxidant; CHEMICAL-COMPOSITION; BACCHARIS-DRACUNCULIFOLIA; GENUS THYMUS; NEROLIDOL; L; VULGARIS; BIOFILM; FLORA; ASSAY; WILD;
D O I
10.1080/14786419.2016.1224874
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The genus Thymus includes several species that are used as flavouring, food preservative as well as in cosmetics. Their secondary metabolites have been extensively studied for pharmacological effects. Nonetheless, some species are neglected and deserve to be explored for chemical composition and biological activities. This is the case with Thymus alternans, a Carpathian bush used as a food additive and for the preparation of a traditional herbal medicine. In this work, we have analysed the chemical composition of T. alternans essential oil by GC and GC-MS and evaluated its antimicrobial and antioxidant activity by disc diffusion, DPPH, ABTS and FRAP methods, respectively. Results showed that T. alternans belongs to the nerolidol chemotype, being rich of this sesquiterpene alcohol (15.8%) which might contribute to the antimicrobial (particularly effective on C. albicans growth) and antioxidant (weak inhibition on ABTS radical and reducing power) activities observed.
引用
收藏
页码:1121 / 1130
页数:10
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