Complete Resolution of Paget Disease of the Vulva With Imiquimod Cream

被引：42

作者：

Hatch, Kenneth D. ^{[1
]}

Davis, John R. ^{[1
]}

机构：

[1] Univ Arizona, Tucson, AZ 85724 USA

来源：

JOURNAL OF LOWER GENITAL TRACT DISEASE | 2008年 / 12卷 / 02期

关键词：

vulva; Paget disease; imiquimod;

D O I：

10.1097/LGT.0b013e31815a58a5

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.

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页码：90 / 94

页数：5

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