Localized Argyria Caused by Metallic Silver Aortic Grafts: A Unique Adverse Effect

被引：8

作者：

Berger, P. ^{[1
]}

Ricco, J. B. ^{[2
]}

Lung, P. Liqui ^{[3
]}

Moll, F. L. ^{[1
]}

机构：

[1] Univ Med Ctr Utrecht, Dept Vasc Surg, NL-3508 GA Utrecht, Netherlands

[2] Univ Med Ctr, Dept Vasc Surg, Poitiers, France

[3] Rivierenland Ziekenhuis, Dept Surg, Tiel, Netherlands

来源：

EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY | 2013年 / 46卷 / 05期

关键词：

Argyria; Adverse effect; Silver grafts; VASCULAR GRAFT; IN-VITRO;

D O I：

10.1016/j.ejvs.2013.07.021

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Introduction: Silver-coated grafts are designed to prevent vascular graft infections. Silver is a safe element but toxic effects have been reported. We describe two cases of possible localized argyria after silver graft implantation. Report: Two patients presented with perigraft groin collections after implantation of silver grafts. During reoperation, an ashen-grey necrotic substance was seen surrounding the grafts. The grafts were explanted and lower limb perfusion restored. Cultures were negative and both patients had uneventful recoveries. Discussion: Our cases are highly suggestive of a possible unique adverse effect: a combination of localized silver toxicity and neutrophilic mediated tissue destruction. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.

引用

页码：565 / 568

页数：4

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