Induction and differentiation of extra-embryonic mesoderm in the mouse

被引:13
|
作者
Boucher, DM
Pedersen, RA
机构
[1] UNIV CALIF SAN FRANCISCO, DEPT ANAT, SAN FRANCISCO, CA 94143 USA
[2] UNIV CALIF SAN FRANCISCO, DEPT RADIOL, SAN FRANCISCO, CA 94143 USA
[3] UNIV CALIF SAN FRANCISCO, DEPT OBSTET GYNECOL & REPROD SCI, SAN FRANCISCO, CA 94143 USA
关键词
ES cells; yolk sac; amnion; chorioallantoic fusion; BMP-4; evx-1; cdx-4; brachyury; eed; FGF; Xwnt-8;
D O I
10.1071/RD9960765
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Extra-embryonic mesoderm, derived at the time of gastrulation from the primitive streak, gives rise to several tissues that function to provide the embryo with nutrients, a means of waste disposal, and mechanical protection. Little is known about the differentiation of this tissue and about the growth and transcription factors involved. The present review focussed on growth and transcription factors that may be involved in differentiation of extra-embryonic mesoderm, and results from fate-mapping and transplantation studies, Methods in vitro available for assaying the effects of growth and transcription factors on development of extra-embryonic development are also discussed.
引用
收藏
页码:765 / 777
页数:13
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