Microstructure and osteoblast response of gradient bioceramic coating on titanium alloy fabricated by laser cladding

被引：38

作者：

Zheng, Min ^{[1
]}

Fan, Ding ^{[1
]}

Li, Xiu-Kun ^{[1
]}

Li, Wen-Fei ^{[2
]}

Liu, Qi-Bin ^{[2
]}

Zhang, Jian-Bin ^{[1
]}

机构：

[1] Lanzhou Univ Technol, State Key Lab Gansu Adv Nonferrous Met Mat, Lanzhou 730050, Peoples R China

[2] Guizhou Univ, Coll Mat Sci & Engn, Guiyang 550003, Peoples R China

来源：

APPLIED SURFACE SCIENCE | 2008年 / 255卷 / 02期

关键词：

Microstructure; Cell proliferation; Bioceramic coating; Laser cladding;

D O I：

10.1016/j.apsusc.2008.06.078

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

To construct a bioactive interface between metal implant and the surrounding bone tissue, the gradient calcium phosphate bioceramic coating on titanium alloy (Ti-6Al-4V) was designed and fabricated by laser cladding. The results demonstrated that the gradient bioceramic coating was metallurgically bonded to the titanium alloy substrate. The appearance of hydroxyapatite and beta-tricalcium phosphate indicated that the bioactive phases were synthesized on the surface of coating. The microhardness gradually decreased from the coating to substrate, which could help stress relaxation between coating and bone tissue. Furthermore, the methyl thiazolyl tetrazolium (MTT) assay of cell proliferation revealed that the laser-cladded bioceramic coating had more favorable osteoblast response compared with the surface of untreated titanium alloy substrate. (c) 2008 Elsevier B. V. All rights reserved.

引用

页码：426 / 428

页数：3

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