Atrial angiotensin-(1-12)/chymase expression data in patient of heart diseases

被引：6

作者：

Wang, Hao ^{[1
,2
]}

Varagic, Jasmina ^{[3
,4
,5
]}

Nagata, Sayaka ^{[3
]}

Kon, Neal D. ^{[6
]}

Ahmad, Sarfaraz ^{[3
]}

VonCannon, Jessica L. ^{[3
]}

Wright, Kendra N. ^{[3
]}

Sun, Xuming ^{[1
]}

Deal, Dwight ^{[6
]}

Groban, Leanne ^{[1
,2
]}

Ferrario, Carlos M. ^{[3
,5
]}

机构：

[1] Wake Forest Sch Med, Dept Anesthesiol, Med Ctr Blvd, Winston Salem, NC 27157 USA

[2] Wake Forest Sch Med, Dept Internal Med Mol Med, Winston Salem, NC 27101 USA

[3] Wake Forest Sch Med, Dept Surg, Winston Salem, NC 27101 USA

[4] Wake Forest Sch Med, Hypertens & Vasc Res Ctr, Winston Salem, NC 27101 USA

[5] Wake Forest Sch Med, Dept Physiol & Pharmacol, Winston Salem, NC 27101 USA

[6] Wake Forest Sch Med, Dept Cardiothorac Surg, Winston Salem, NC 27101 USA

来源：

DATA IN BRIEF | 2020年 / 31卷

基金：

美国国家卫生研究院;

关键词：

chymase; angiotensin-(1-12); angiotensin II; human; heart disease; atria;

D O I：

10.1016/j.dib.2020.105744

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The data presented here are related to the research article entitled "Differential expression of the angiotensin-(112) [Ang-(1-12)]/chymase axis in human atrial tissue [1] . We have showed that chymase gene transcripts, chymase activity, and immunoreactiveAng-(1-12) expression levels were higher in left compared to right atrial tissue, irrespective of cardiac disease. This article presents the echocardiographic characteristics of 111 patients undergoing heart surgery for the correction of valvular heart disease, resistant atrial fibrillation or ischemic heart disease. Left atrial chymase mRNA expression and activity, and left atrial Ang-(1-12) levels were compared between patients with stroke vs. non-stroke, congestive heart failure vs. non-heart failure, and in cardiac surgery patients who had a history of postoperative atrial fib-rillation vs. non-atrial fibrillation. (c) 2020 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license. ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )

引用

页数：7

共 5 条

[1] Chymase mediates angiotensin-(1-12) metabolism in normal human hearts
Ahmad, Sarfaraz
Wei, Chih-Chang
Tallaj, Jose
Dell'Italia, Louis J.
Moniwa, Norihito
Varagic, Jasmina
Ferrario, Carlos M.
[J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2013, 7 (02) : 128 - 136
[2] Chymase-Dependent Generation of Angiotensin II from Angiotensin-(1-12) in Human Atrial Tissue
Ahmad, Sarfaraz
Simmons, Tony
Varagic, Jasmina
Moniwa, Norihito
Chappell, Mark C.
Ferrario, Carlos M.
[J]. PLOS ONE, 2011, 6 (12):
[3] Recommendations for chamber quantification: A report from the American Society of Echocardiography's guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology
Lang, RM
Bierig, M
Devereux, RB
Flachskampf, FA
Foster, E
Pellikka, PA
Picard, MH
Roman, MJ
Seward, J
Shanewise, JS
Solomon, SD
Spencer, KT
Sutton, MS
Stewart, WJ
[J]. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, 2005, 18 (12) : 1440 - 1463
[4] TISSUE ANGIOTENSIN-II SYSTEM IN THE HUMAN HEART
URATA, H
HOFFMANN, S
GANTEN, D
[J]. EUROPEAN HEART JOURNAL, 1994, 15 : 68 - 78
[5] Wang H., J SURG RES UNPUB

← 1 →