Copper catalyzed cyclopropanation of 1,2,3,4-tetrahydropyridin-2-ones with trimethylsilyldiazomethane: A facile and selective synthesis of 2-aza-3-oxobicyclo[4.1.0] heptanes

被引：0

作者：

Sharma, VB ^{[1
]}

Jain, SL ^{[1
]}

Sain, B ^{[1
]}

机构：

[1] Indian Inst Petr, Chem & Biotechnol Div, Dehra Dun 248005, Uttar Pradesh, India

来源：

HETEROCYCLES | 2006年 / 68卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of a series of 1,2,3,4-tetrahydropyridin-2-ones with trimethylsilyldiazomethane using catalytic amounts of copper(II) triflate in refluxing 1,2-dichloroethane yielded exclusively 3-oxo-2-azabicyclo[4.1.0]-heptanes in good yields. The application of ultrasonic radiation enhanced the reaction rate and allowed the reactions to be conducted at room temperature.

引用

页码：475 / 481

页数：7

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