Visual Symptoms in Parkinson's Disease

被引:121
作者
Armstrong, R. A. [1 ]
机构
[1] Aston Univ, Dept Vis Sci, Birmingham B4 7ET, W Midlands, England
关键词
MULTIPLE SYSTEM ATROPHY; EVOKED-POTENTIALS; CONTRAST SENSITIVITY; PATTERN ELECTRORETINOGRAM; DOPAMINERGIC DEFICIENCY; EYE-MOVEMENTS; ALZHEIMERS-DISEASE; SUBSTANTIA-NIGRA; RETINAL DOPAMINE; BASAL GANGLIA;
D O I
10.4061/2011/908306
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Parkinson's disease (PD) is a common disorder of middle-aged and elderly people in which degeneration of the extrapyramidal motor system causes significant movement problems. In some patients, however, there are additional disturbances in sensory systems including loss of the sense of smell and auditory and/or visual problems. This paper is a general overview of the visual problems likely to be encountered in PD. Changes in vision in PD may result from alterations in visual acuity, contrast sensitivity, colour discrimination, pupil reactivity, eye movements, motion perception, visual field sensitivity, and visual processing speeds. Slower visual processing speeds can also lead to a decline in visual perception especially for rapidly changing visual stimuli. In addition, there may be disturbances of visuospatial orientation, facial recognition problems, and chronic visual hallucinations. Some of the treatments used in PD may also have adverse ocular reactions. The pattern electroretinogram (PERG) is useful in evaluating retinal dopamine mechanisms and in monitoring dopamine therapies in PD. If visual problems are present, they can have an important effect on the quality of life of the patient, which can be improved by accurate diagnosis and where possible, correction of such defects.
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页数:9
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