Chemical Constituents and Antioxidant Activity from the Stems of Alyxia reinwardtii

被引:0
作者
Rattanapan, Jurairat [1 ]
Sichaem, Jirapast [1 ,2 ]
Tip-pyang, Santi [1 ]
机构
[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Nat Prod Res Unit, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Ctr Petr Petrochem & Adv Mat, Bangkok 10330, Thailand
关键词
Alyxia reinwardtii; Apocynaceae; DPPH; xanthine oxidase-related activity; lipid peroxidation inhibitory activity; TRADITIONAL MEDICINAL-PLANTS; THAILAND; LIGNANS;
D O I
暂无
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Eight compounds were isolated from the stems of Alyxia reinwardtii, namely coumarin (1), 3-hydroxycoumarin (2), 6-hydroxycoumarin (3), 8-hydroxycoumarin (4), scopoletin (5), (+)-pinoresinol (6), zhebeiresinol (7) and p-hydroxybenzoic acid (8). The structures of all compounds were characterized by means of NMR, MS, chemical analysis and comparison with the literature data. The structure of compound 7 was also confirmed by X-ray crystallography. To the best of our knowledge, compounds 2-3, 5 and 7-8 have been isolated for the first time from this species. In terms of antioxidant activity, the isolated compounds were evaluated by various in vitro model assays, which include the DPPH radical scavenging activity, xanthine oxidase-related activity (superoxide scavenging activity and inhibitory effect on xanthine oxidase) and lipid peroxidation inhibitory activity.
引用
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页码:288 / 291
页数:4
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