Management of CMV, HHV-6, HHV-7 and Kaposi-sarcoma herpesvirus (HHV-8) infections in patients with hematological malignancies and after SCT

被引:195
作者
Ljungman, P. [1 ]
de la Camara, R. [1 ]
Cordonnier, C. [1 ]
Einsele, H. [1 ]
Engelhard, D. [1 ]
Reusser, P. [1 ]
Styczynski, J. [1 ]
Ward, K. [1 ]
机构
[1] Karolinska Univ, Huddinge Hosp, Dept Hematol, S-14186 Huddinge, Sweden
关键词
CMV; HHV-6; HHV-7; HHV-8; SCT; antiviral drugs;
D O I
10.1038/bmt.2008.162
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
These recommendations were prepared by the European Conference on Infections in Leukaemia following a predefined methodology. Literature searches were made to identify studies pertinent to management of CMV, HHV-6, -7 and -8 infections. For CMV, 76 studies were reviewed: 72 published and 4 presented as abstracts. Twenty-nine of these studies were prospective randomized trials. For the other herpesviruses, HHV-6, -7 and -8, no randomized controlled trial has been performed, although data from some studies with other primary endpoints have been used to assess the management of HHV-6 infection. Works presented only as abstracts were used to a very limited extent. The quality of evidence and level of recommendation were graded according to the Center for Disease Control (CDC) criteria.
引用
收藏
页码:227 / 240
页数:14
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