Beyond obesity: Is cholesterol-induced liver injury the cause of non-alcoholic steatohepatitis?

被引：5

作者：

Ioannou, George N. ^{[1
,2
]}

机构：

[1] Vet Affairs Puget Sound Hlth Care Syst, Div Gastroenterol, Seattle, WA 98108 USA

[2] Univ Washington, Seattle, WA 98195 USA

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2012年 / 27卷 / 09期

关键词：

DIETARY-CHOLESTEROL; MICE; INFLAMMATION; STEATOSIS; FIBROSIS;

D O I：

10.1111/j.1440-1746.2012.07196.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

See article in J. Gastroenterol. Hepatol. 2012; 27: 15201527.

引用

页码：1412 / 1414

页数：3

共 11 条

[1] Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity [J].

Adams, Leon A. ;

Marsh, Julie A. ;

Ayonrinde, Oyekoya T. ;

Olynyk, John K. ;

Ang, Wei Q. ;

Beilin, Lawrence J. ;

Mori, Trevor ;

Palmer, Lyle J. ;

Oddy, Wendy W. ;

Lye, Steven J. ;

Pennell, Craig E. .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2012, 27 (09) :1520-1527

[2] Association Between Dietary Nutrient Composition and the Incidence of Cirrhosis or Liver Cancer in the United States Population [J].

Ioannou, George N. ;

Morrow, Olivia B. ;

Connole, Marah L. ;

Lee, Sum P. .

HEPATOLOGY, 2009, 50 (01) :175-184

[3] Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease [J].

Park, Hyohun ;

Shima, Toshihide ;

Yamaguchi, Kanji ;

Mitsuyoshi, Hironori ;

Minami, Masahito ;

Yasui, Kohichiroh ;

Itoh, Yoshito ;

Yoshikawa, Toshikazu ;

Fukui, Michiaki ;

Hasegawa, Goji ;

Nakamura, Naoto ;

Ohta, Mitsuhiro ;

Obayashi, Hiroshi ;

Okanoue, Takeshi .

JOURNAL OF GASTROENTEROLOGY, 2011, 46 (01) :101-107

[4]

Savard C, 2012, HEPTAOLOGY, DOI [10.1002/hep.25800, DOI 10.1002/HEP.25800]

[5] Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice [J].

Subramanian, Savitha ;

Goodspeed, Leela ;

Wang, Shari ;

Kim, Jinkyu ;

Zeng, Lixia ;

Ioannou, George N. ;

Haigh, W. Geoffrey ;

Yeh, Matthew M. ;

Kowdley, Kris V. ;

O'Brien, Kevin D. ;

Pennathur, Subramaniam ;

Chait, Alan .

JOURNAL OF LIPID RESEARCH, 2011, 52 (09) :1626-1635

[6] A High-Cholesterol Diet Exacerbates Liver Fibrosis in Mice via Accumulation of Free Cholesterol in Hepatic Stellate Cells [J].

Teratani, Toshiaki ;

Tomita, Kengo ;

Suzuki, Takahiro ;

Oshikawa, Tetsuya ;

Yokoyama, Hirokazu ;

Shimamura, Katsuyoshi ;

Tominaga, Susumu ;

Hiroi, Sadayuki ;

Irie, Rie ;

Okada, Yoshikiyo ;

Kurihara, Chie ;

Ebinuma, Hirotoshi ;

Saito, Hidetsugu ;

Hokari, Ryota ;

Sugiyama, Kazuo ;

Kanai, Takanori ;

Miura, Soichiro ;

Hibi, Toshifumi .

GASTROENTEROLOGY, 2012, 142 (01) :152-U331

[7] Homozygosity for the Patatin-Like Phospholipase-3/Adiponutrin I148M Polymorphism Influences Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease [J].

Valenti, Luca ;

Al-Serri, Ahmad ;

Daly, Ann K. ;

Galmozzi, Enrico ;

Rametta, Raffaela ;

Dongiovanni, Paola ;

Nobili, Valerio ;

Mozzi, Enrico ;

Roviaro, Giancarlo ;

Vanni, Ester ;

Bugianesi, Elisabetta ;

Maggioni, Marco ;

Fracanzani, Anna Ludovica ;

Fargion, Silvia ;

Day, Christopher P. .

HEPATOLOGY, 2010, 51 (04) :1209-1217

[8] Hepatic Free Cholesterol Accumulates in Obese, Diabetic Mice and Causes Nonalcoholic Steatohepatitis [J].

van Rooyen, Derrick M. ;

Larter, Claire Z. ;

Haigh, W. Geoffrey ;

Yeh, Matthew M. ;

Ioannou, George ;

Kuver, Rahul ;

Lee, Sum P. ;

Teoh, Narci C. ;

Farrell, Geoffrey C. .

GASTROENTEROLOGY, 2011, 141 (04) :1393-U850

[9] Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis [J].

Wouters, Kristiaan ;

van Gorp, Patrick J. ;

Bieghs, Veerle ;

Gijbels, Marion J. ;

Duimel, Hans ;

Luetjohann, Dieter ;

Kerksiek, Anja ;

van Kruchten, Roger ;

Maeda, Nobuyo ;

Staels, Bart ;

van Bilsen, Marc ;

Shiri-Sverdlov, Ronit ;

Hofker, Marten H. .

HEPATOLOGY, 2008, 48 (02) :474-486

[10] Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice [J].

Wouters, Kristiaan ;

van Bilsen, Marc ;

van Gorp, Patrick J. ;

Bieghs, Veerle ;

Luetjohann, Dieter ;

Kerksiek, Anja ;

Staels, Bart ;

Hofker, Marten H. ;

Shiri-Sverdlov, Ronit .

FEBS LETTERS, 2010, 584 (05) :1001-1005

← 1 2 →