Lead revision surgery for vagus nerve stimulation in epilepsy: Outcomes and efficacy

被引:12
作者
Waseem, Hena [1 ]
Raffa, Scott J. [1 ]
Benbadis, Selim R. [2 ]
Vale, Fernando L. [1 ]
机构
[1] Univ S Florida, Morsani Coll Med, Dept Neurosurg & Brain Repair, USF Hlth, Tampa, FL 33606 USA
[2] Univ S Florida, Morsani Coll Med, Dept Neurol, USF Hlth, Tampa, FL 33606 USA
关键词
Vagus nerve stimulation; Intractable epilepsy; Seizure disorder; Epilepsy surgery; Lead revision; THERAPY; ELECTRODES; SEIZURES; CHILDREN;
D O I
10.1016/j.yebeh.2013.12.002
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
We present, to our knowledge, the first published analysis of vagus nerve stimulation (VNS) lead revisions to incorporate quality of life, clinical response, and antiepileptic drug (AED) burden in postrevision clinical outcomes. Ten patients were followed and had no postoperative complications. Seven patients had improvement in quality of life, and three experienced no change. Eight patients noted a restoration of clinical response comparable with initial VNS implantation. Seven patients reported 30-60% improvement in seizure reduction, two experienced N60%, and one noted < 30%. Six patients had no change in AED burden. Vagus nerve stimulation lead revision should be considered a safe option for patients with VNS lead failure and medically intractable epilepsy. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:110 / 113
页数:4
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