Biomarkers and creatinine in AKI: the trough of disillusionment or the slope of enlightenment?

被引：22

作者：

Endre, Zoltan H. ^{[1
,2
]}

Pickering, John W. ^{[1
]}

机构：

[1] Univ Otago Christchurch, Christchurch Kidney Res Grp, Dept Med, Christchurch, New Zealand

[2] Univ New S Wales, Prince Wales Clin Sch, Dept Nephrol, Sydney, NSW, Australia

来源：

KIDNEY INTERNATIONAL | 2013年 / 84卷 / 04期

关键词：

ACUTE KIDNEY INJURY; INTENSIVE-CARE-UNIT; URINARY BIOMARKERS; CARDIAC-SURGERY; CYSTATIN C; ARREST;

D O I：

10.1038/ki.2013.168

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Assessment of acute kidney biomarkers against changes in plasma creatinine is beset by issues of heterogeneity of study cohorts and timing of sampling. Siew and colleagues attempt to minimize these issues in a case-control study of three biomarkers in the intensive care unit. The results highlight the inherent methodological difficulties and the need to reference structural injury biomarkers against more meaningful outcomes.

引用

页码：644 / 647

页数：4

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