Practical Management of Inflammatory Bowel Disease in Childhood
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作者:
Beattie, R. M.
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Southampton Gen Hosp, Pediat Med Unit, Southampton SO 16 16YD, Hants, EnglandSouthampton Gen Hosp, Pediat Med Unit, Southampton SO 16 16YD, Hants, England
Beattie, R. M.
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机构:
[1] Southampton Gen Hosp, Pediat Med Unit, Southampton SO 16 16YD, Hants, England
25 % of inflammatory bowel disease presents in childhood, often in adolescence, and usually as Crohn's disease or ulcerative colitis. Family history is common. The diseases run a chronic relapsing course, with a significant disease burden particularly during the adolescent growth spurt. Growth and nutrition are key issues with the aim of treatment being given to induce and then maintain disease remission with minimal side effects. Specific management strategies include exclusive enteral nutrition, antibiotics, 5 ASA derivatives, corticosteroids, thiopurine derivatives, second line immunosuppressive agents such as anti-tumor necrosis antibody therapy and surgery.
机构:
Univ London Royal Free Hosp, Dept Paediat Gastroenterol, London NW3 2QG, EnglandUniv London Royal Free Hosp, Dept Paediat Gastroenterol, London NW3 2QG, England
Heuschkel, RB
Walker-Smith, JA
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Univ London Royal Free Hosp, Dept Paediat Gastroenterol, London NW3 2QG, EnglandUniv London Royal Free Hosp, Dept Paediat Gastroenterol, London NW3 2QG, England
机构:
Southampton Gen Hosp, NIHR Biomed Res Unit Nutr Diet & Lifestyle, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Wiskin, Anthony E.
Wootton, Stephen A.
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Southampton Gen Hosp, NIHR Biomed Res Unit Nutr Diet & Lifestyle, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Wootton, Stephen A.
Hunt, Toby M.
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Southampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Hunt, Toby M.
Cornelius, Victoria R.
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Southampton Gen Hosp, NIHR Biomed Res Unit Nutr Diet & Lifestyle, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Cornelius, Victoria R.
Afzal, Nadeem A.
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Southampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Afzal, Nadeem A.
Jackson, Alan A.
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Southampton Gen Hosp, NIHR Biomed Res Unit Nutr Diet & Lifestyle, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England
Jackson, Alan A.
Beattie, R. Mark
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Southampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, EnglandSouthampton Gen Hosp, Paediat Med Unit, Southampton SO16 6YD, Hants, England