Next-generation adenoviral vectors: new and improved

被引:24
作者
Amalfitano, A
机构
[1] Duke Univ, Med Ctr, Dept Pediat, Div Med Genet, Durham, NC 27710 USA
[2] Duke Univ, Med Ctr, Dept Genet, Durham, NC 27710 USA
关键词
D O I
10.1038/sj.gt.3301027
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1643 / 1645
页数:3
相关论文
共 17 条
[1]   Isolation and characterization of packaging cell lines that coexpress the adenovirus E1, DNA polymerase, and preterminal proteins: Implications for gene therapy [J].
Amalfitano, A ;
Chamberiain, JS .
GENE THERAPY, 1997, 4 (03) :258-263
[2]   Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors [J].
Amalfitano, A ;
Begy, CR ;
Chamberlain, JS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (08) :3352-3356
[3]   Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted [J].
Amalfitano, A ;
Hauser, MA ;
Hu, HM ;
Serra, D ;
Begy, CR ;
Chamberlain, JS .
JOURNAL OF VIROLOGY, 1998, 72 (02) :926-933
[4]   Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo [J].
Brough, DE ;
Hsu, C ;
Kulesa, VA ;
Lee, GM ;
Cantolupo, LJ ;
Lizonova, A ;
Kovesdi, I .
JOURNAL OF VIROLOGY, 1997, 71 (12) :9206-9213
[5]   Persistence in muscle of an adenoviral vector that lacks all viral genes [J].
Chen, HH ;
Mack, LM ;
Kelly, R ;
Ontell, M ;
Kochanek, S ;
Clemens, PR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (05) :1645-1650
[6]   Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses [J].
Dedieu, JF ;
Vigne, E ;
Torrent, C ;
Jullien, C ;
Mahfouz, I ;
Caillaud, JM ;
Aubailly, N ;
Orsini, C ;
Guillaume, JM ;
Opolon, P ;
Delaere, P ;
Perricaudet, M ;
Yeh, P .
JOURNAL OF VIROLOGY, 1997, 71 (06) :4626-4637
[7]   Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy [J].
Gao, GP ;
Yang, YP ;
Wilson, JM .
JOURNAL OF VIROLOGY, 1996, 70 (12) :8934-8943
[8]   Construction of adenovirus vectors through Cre-lox recombination [J].
Hardy, S ;
Kitamura, M ;
HarrisStansil, T ;
Dai, YM ;
Phipps, ML .
JOURNAL OF VIROLOGY, 1997, 71 (03) :1842-1849
[9]   Persistence of an [E1-, polymerase-] adenovirus vector despite transduction of a neoantigen into immune-competent mice [J].
Hu, HM ;
Serra, D ;
Amalfitano, A .
HUMAN GENE THERAPY, 1999, 10 (03) :355-364
[10]   Adenoviral preterminal protein stabilizes mini-adenoviral genomes in vitro and in vivo [J].
Lieber, A ;
He, CY ;
Kay, MA .
NATURE BIOTECHNOLOGY, 1997, 15 (13) :1383-1387