Total synthesis of norleucosceptroids F and G

被引:7
|
作者
Xu, Jiao [1 ]
Liu, Bo [1 ,2 ]
机构
[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Peoples R China
[2] China Pharmaceut Univ, State Key Lab Natl Med, Nanjing 210009, Peoples R China
基金
中国国家自然科学基金;
关键词
Total synthesis; Norleucosceptroid F; Norleucosceptroid G; LEUCOSCEPTRUM-CANUM; DEFENSIVE SESTERTERPENOIDS; GLANDULAR TRICHOMES; NATURAL-PRODUCTS; TERPENOIDS; HARBOR; MODEL;
D O I
10.1016/j.cclet.2015.07.004
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
First total synthesis of norleucosceptroids F and G has been achieved through key steps of Michael-Aldol cascade, oxa-Michael cyclization-dehydration-deprotection cascade and cross metathesis (CM), this work developed a general and concise method to the synthesis of leucosceptroid and norleucosceptroid. (C) 2015 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:1341 / 1344
页数:4
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