Diabetes mellitus, high BMI and low education level predict sudden cardiac death within 24 hours of incident myocardial infarction

被引:20
作者
Andersson, Jonas [1 ]
Wennberg, Patrik [2 ]
Lundblad, Dan [3 ]
Escher, Stefan A. [4 ]
Jansson, Jan-Hakan [1 ]
机构
[1] Umea Univ, Dept Publ Hlth & Clin Med, Skelleftea Res Unit, Umea, Sweden
[2] Umea Univ, Dept Publ Hlth & Clin Med, Family Med, Umea, Sweden
[3] Umea Univ, Dept Publ Hlth & Clin Med, Sunderby Res Unit, Umea, Sweden
[4] Lund Univ, Ctr Diabet, Genet & Mol Epidemiol Unit, Lund, Sweden
关键词
Sudden cardiac death; epidemiology; myocardial infarction; risk factors; prevention; prognosis; CORONARY-HEART-DISEASE; RISK STRATIFICATION; CASE-FATALITY; ARREST; PREVENTION; SWEDEN; PATHOGENESIS; ASSOCIATION; POPULATION; MORTALITY;
D O I
10.1177/2047487316659574
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Vasterbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in northern Sweden (1986-2006). To determine predictors for sudden cardiac death risk factors for cardiovascular disease were compared between incident myocardial infarction with sudden cardiac death (n=363) and survivors of incident myocardial infarction (n=1998) using multivariate logistic regression analysis. Results Diabetes had the strongest association with sudden cardiac death out of all evaluated risk factors (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.30-2.59), followed by low education (OR 1.55, 95% CI 1.19-2.01), high body mass index (OR 1.05, 95% CI 1.02-1.08) and male sex (OR 1.42, 95% CI 1.001-2.01). Conclusions The pattern of risk factors for incident myocardial infarction is different among survivors and those who die within 24 hours. The risk factors that contribute the most to death within 24 hours are diabetes mellitus, high body mass index and low education level, and can be addressed at both the public health level and by general practitioners.
引用
收藏
页码:1814 / 1820
页数:7
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