Growing better blood vessels - A polymer scaffold that delivers two angiogenic factors with distinct kinetics shows promise for engineering mature blood vessels

被引:62
作者
Carmeliet, P
Conway, EM
机构
[1] Katholieke Univ Leuven, Louvain, Belgium
[2] Flanders Interuniv Inst Biotechnol, Louvain, Belgium
关键词
D O I
10.1038/nbt1101-1019
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:1019 / 1020
页数:2
相关论文
共 12 条
[1]   Somatic gene therapy in the cardiovascular system [J].
Baumgartner, I ;
Isner, JM .
ANNUAL REVIEW OF PHYSIOLOGY, 2001, 63 :427-450
[2]  
Benjamin LE, 1998, DEVELOPMENT, V125, P1591
[3]   Developmental roles of platelet-derived growth factors [J].
Betsholtz, C ;
Karlsson, L ;
Lindahl, P .
BIOESSAYS, 2001, 23 (06) :494-507
[4]   The well-tempered vessel [J].
Blau, HM ;
Banfi, A .
NATURE MEDICINE, 2001, 7 (05) :532-534
[5]   VEGF gene therapy: stimulating angiogenesis or angioma-genesis? [J].
Carmeliet, P .
NATURE MEDICINE, 2000, 6 (10) :1102-1103
[6]   Mechanisms of angiogenesis and arteriogenesis [J].
Carmeliet, P .
NATURE MEDICINE, 2000, 6 (04) :389-395
[7]   Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele [J].
Carmeliet, P ;
Ferreira, V ;
Breier, G ;
Pollefeyt, S ;
Kieckens, L ;
Gertsenstein, M ;
Fahrig, M ;
Vandenhoeck, A ;
Harpal, K ;
Eberhardt, C ;
Declercq, C ;
Pawling, J ;
Moons, L ;
Collen, D ;
Risau, W ;
Nagy, A .
NATURE, 1996, 380 (6573) :435-439
[8]   Angiogenesis therapy - Amidst the hype, the neglected potential for serious side effects [J].
Epstein, SE ;
Kornowski, R ;
Fuchs, S ;
Dvorak, HF .
CIRCULATION, 2001, 104 (01) :115-119
[9]   Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis [J].
Hellström, M ;
Gerhardt, H ;
Kalén, M ;
Li, XR ;
Eriksson, U ;
Wolburg, H ;
Betsholtz, C .
JOURNAL OF CELL BIOLOGY, 2001, 153 (03) :543-553
[10]   Polymeric system for dual growth factor delivery [J].
Richardson, TP ;
Peters, MC ;
Ennett, AB ;
Mooney, DJ .
NATURE BIOTECHNOLOGY, 2001, 19 (11) :1029-1034