High Prevalence of Nasopharyngeal Colonization by Staphylococcus aureus Among Children with HIV-1 Infection in Extreme Southern Brazil

被引：5

作者：

D'Avila, Nildo E. M. ^{[1
]}

Zhang, Linjie ^{[1
]}

Miller, Roger G. ^{[2
]}

D'Avila, Alan C.

Conceicao, Ana P. C.

Boffo, Manoela S. ^{[1
]}

机构：

[1] Fed Univ Rio Grande, Dept Maternal & Child Hlth, Rio Grande, RS, Brazil

[2] Fed Univ Rio Grande, Clin Lab, Rio Grande, RS, Brazil

来源：

JOURNAL OF TROPICAL PEDIATRICS | 2008年 / 54卷 / 06期

关键词：

D O I：

10.1093/tropej/fmn051

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Objectives: To compare nasopharyngeal colonization between children with HIV-1 infection and those without HIV-1 infection, with special emphasis on nasopharyngeal carriage of Staphylococcus aureus. Methods: This hospital-based cross-sectional study was carried out in the Paediatric Day Hospital of a teaching hospital. Nasopharyngeal swabs were collected in 93 children aged up to 18 years old born to HIV-positive mothers (31 children with HIV-1 infection and 62 age-matched non-infected children). Results: The prevalence of nasopharyngeal colonization by S. aureus was higher among children with HIV-1 infection compared with those without HIV-1 infection (45.16 vs. 12.9, p 0.001). After adjusting all potential confounders, HIV-1 infection was an independent risk factor for nasopharyngeal colonization by S. aureus, with a prevalence ratio of 4.29 (95 confidence interval: 1.7210.70). Conclusion: Children with HIV-1 infection had a higher prevalence of nasopharyngeal colonization by S. aureus than children without HIV-1 infection. Most of the isolated strains of S. aureus were methicillin-susceptible.

引用

页码：410 / 412

页数：3

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