Costs and Outcomes of Increasing Access to Bariatric Surgery: Cohort Study and Cost-Effectiveness Analysis Using Electronic Health Records

被引:72
作者
Gulliford, Martin C. [1 ,2 ]
Charlton, Judith [1 ]
Prevost, Toby [1 ,2 ]
Booth, Helen [1 ]
Fildes, Alison [1 ]
Ashworth, Mark [1 ]
Littlejohns, Peter [1 ]
Reddy, Marcus [3 ]
Khan, Omar [3 ]
Rudisill, Caroline [4 ]
机构
[1] Kings Coll London, Dept Primary Care & Publ Hlth Sci, Addison House,Guys Campus, London SE1 1UL, England
[2] Guys & St Thomas Natl Hlth Serv Fdn Trust, Natl Inst Hlth Res, Biomed Res Ctr, London, England
[3] Natl Hlth Serv Fdn Trust, St Georges Univ Hosp, Dept Surg, London, England
[4] London Sch Econ & Polit Sci, Dept Social Policy, London, England
关键词
bariatric surgery; cost-effectiveness analysis; diabetes mellitus; obesity; SWEDISH OBESE SUBJECTS; BODY-MASS INDEX; CONTROLLED INTERVENTION; CARE COSTS; ASSOCIATION; MORTALITY; IMPACT;
D O I
10.1016/j.jval.2016.08.734
中图分类号
F [经济];
学科分类号
02 ;
摘要
Objectives: To estimate costs and outcomes of increasing access to bariatric surgery in obese adults and in population subgroups of age, sex, deprivation, comorbidity, and obesity category. Methods: A cohort study was conducted using primary care electronic health records, with linked hospital utilization data, for 3,045 participants who underwent bariatric surgery and 247,537 participants who did not undergo bariatric surgery. Epidemiological analyses informed a probabilistic Markov model to compare bariatric surgery, including equal proportions with adjustable gastric banding, gastric bypass, and sleeve gastrectomy, with standard nonsurgical management of obesity. Outcomes were quality-adjusted life-years (QALYs) and net monetary benefits at a threshold of 30,000 per QALY. Results: In a UK population of 250,000 adults, there may be 7,163 people with morbid obesity including 1,406 with diabetes. The immediate cost of 1,000 bariatric surgical procedures is 9.16 million, with incremental discounted lifetime health care costs of 15.26 million (95% confidence interval 15.18- 15.36 million). Patient-years with diabetes mellitus will decrease by 8,320 (range 8,123-8,502). Incremental QALYs will increase by 2,142 (range 2,032-2,256). The estimated cost per QALY gained is 7,129 (range 6,775- 7,506). Net monetary benefits will be 49.02 million (range 45.72- 52.41 million). Estimates are similar for subgroups of age, sex, and deprivation. Bariatric surgery remains costeffective if the procedure is twice as costly, or if intervention effect declines over time. Conclusions: Diverse obese individuals may benefit from bariatric surgery at acceptable cost. Bariatric surgery is not cost-saving, but increased health care costs are exceeded by health benefits to obese individuals.
引用
收藏
页码:85 / 92
页数:8
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