Alterations in milk metabolome and coagulation ability during the lactation of dairy cows

被引:18
作者
Harzia, H. [1 ,2 ,3 ]
Ilves, A. [1 ,2 ,3 ]
Ots, M. [1 ,2 ]
Henno, M. [1 ]
Joudu, I. [1 ,2 ]
Kaart, T. [1 ,2 ]
Ling, K. [1 ]
Kaert, O. [1 ]
Kilk, K. [3 ]
Soomets, U. [3 ]
机构
[1] Estonian Univ Life Sci, Inst Vet Med & Anim Sci, EE-51014 Tartu, Estonia
[2] Biocompetence Ctr Hlth Dairy Prod, EE-51014 Tartu, Estonia
[3] Univ Tartu, Fac Med, Ctr Excellence Translat Med, Dept Biochem, EE-50411 Tartu, Estonia
关键词
lactation curve; milk metabolite; coagulation; HOLSTEIN-FRIESIAN COWS; BOVINE-MILK; GENETIC-PARAMETERS; YIELD; PROFILES; STAGE; TRAITS; CATTLE; BREED;
D O I
10.3168/jds.2013-6808
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Milk composition has been known to change during lactation. To help understand the changes in metabolic profile throughout the whole lactation, liquid chromatography mass-spectrometry was used to analyze 306 milk samples from 82 primi- and multiparous dairy cows. Changes in metabolic profile common to all cows throughout lactation were ascertained based on principal component and general linear model analysis. Sets of specific markers; for instance, 225, 397, and 641-642 m/z (positive mode), and 186, 241, and 601-604 (negative mode), with at least a 1.5-fold higher intensity during the first 60 d compared with the last 60 d of lactation were observed. The metabolome was affected by parity and milking time. Markers, identified as peptides differentiating parity, were observed. A significant increase for citrate was observed in evening milk Milk coagulation traits were strongly animal specific. The curd firmness values were influenced by milking time. Sets of markers were associated with curd firmness in positive (197 m/z) and negative (612, 737, 835, 836, 902, 1000, 1038, and 1079 m/z) ion mode.
引用
收藏
页码:6440 / 6448
页数:9
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