COVID-19-Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attack?

被引：22

作者：

Arnold, Ruth H. ^{[1
]}

机构：

[1] Orange Hlth Serv, Orange, NSW, Australia

来源：

HEART LUNG AND CIRCULATION | 2020年 / 29卷 / 07期

关键词：

COVID; 19; Renin angiotensin system; Angiotensin converting enzyme inhibitors; Angiotensin receptor blockers; Neprilysin; Vitamin D; CONVERTING ENZYME; EXPRESSION;

D O I：

10.1016/j.hlc.2020.05.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Debate continues in the medical literature on the role of the renin angiotensin system (RAS) in Coronavirus disease 2019 (COVID-19) pathophysiology and the implications for the use of cardiovascular drugs acting on the RAS. Could these drugs - which include angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptors blockers (ARBs) - be harmful or potential key therapeutic agents in COVID-19? And, could potentially helpful measures be available and in plain view on the pharmacy shelf?

引用

页码：964 / 972

页数：9

共 54 条

[1] Are vitamin D receptor agonists like angiotensin-converting enzyme inhibitors without side effects? [J].