Maize provitamin A carotenoids, current resources, and future metabolic engineering challenges

被引：88
作者：
Wurtzel, Eleanore T. [1 ,2 ]
Cuttriss, Abby [1 ,3 ]
Vallabhaneni, Ratnakar [1 ,2 ]
机构：
[1] CUNY Herbert H Lehman Coll, Dept Biol Sci, Bronx, NY 10468 USA
[2] CUNY Grad Sch & Univ Ctr, New York, NY 10036 USA
[3] Univ Hawaii, Dept Biol, Hilo, HI 96720 USA
来源：
FRONTIERS IN PLANT SCIENCE | 2012年 / 3卷
基金：
美国国家卫生研究院; 美国国家科学基金会; 美国农业部;
关键词：
carotenoids; maize; vitamin A; metabolic engineering; endosperm; Poaceae; beta-carotene; SYNTHASE GENE FAMILY; PHYTOENE-SYNTHASE; ISOPRENOID BIOSYNTHESIS; BETA-CAROTENE; ACCUMULATION; PATHWAY; ENDOSPERM; LOCUS; RICE; DESATURASE;
D O I：
10.3389/fpls.2012.00029
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Vitamin A deficiency is a serious global health problem that can be alleviated by improved nutrition. Development of cereal crops with increased provitamin A carotenoids can provide a sustainable solution to eliminating vitamin A deficiency worldwide. Maize is a model for cereals and a major staple carbohydrate source. Here, we discuss maize carotenogenesis with regard to pathway regulation, available resources, and current knowledge for improving carotenoid content and levels of provitamin A carotenoids in edible maize endosperm. This knowledge will be applied to improve the nutritional composition of related Poaceae crops. We discuss opportunities and challenges for optimizing provitamin A carotenoid biofortification of cereal food crops.
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页数：12
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