OXA-163-Producing Klebsiella pneumoniae in Cairo, Egypt, in 2009 and 2010

被引：29

作者：

Abdelaziz, Mohammed O. ^{[2
]}

Bonura, Celestino ^{[1
]}

Aleo, Aurora ^{[1
]}

El-Domany, Ramadan A. ^{[2
]}

Fasciana, Teresa ^{[1
]}

Mammina, Caterina ^{[1
]}

机构：

[1] Univ Palermo, Dept Sci Hlth Promot G DAlessandro, Palermo, Italy

[2] Helwan Univ, Dept Microbiol & Immunol, Fac Pharm, Cairo, Egypt

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 07期

关键词：

BETA-LACTAMASE; CARBAPENEMASE; RESISTANCE; SPREAD; ERTAPENEM;

D O I：

10.1128/JCM.06710-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Two genetically unrelated OXA-163-carrying Klebsiella pneumoniae strains were identified from two infection cases in June 2009 and May 2010 in Cairo, Egypt. OXA-163-producing Enterobacteriaceae had been previously reported in Argentina only. Both patients had no history of travel abroad. The emergence of this newly recognized OXA-48-related beta-lactamase able to hydrolyze cephalosporins and carbapenems is especially worrying in a geographic area where OXA-48 is endemic and effective surveillance for antibiotic resistance is largely unaffordable.

引用

页码：2489 / 2491

页数：3

共 18 条

[1]

[Anonymous], 2011, Performance standards for antimicrobial disk susceptibility tests

[2]

approved standard M2-A11, V11th

[3] First detection of oxacillinase-mediated resistance to carbapenems in Klebsiella pneumoniae from Morocco [J].

Benouda, A. ;

Touzani, O. ;

Khairallah, M. -T. ;

Araj, G. F. ;

Matar, G. M. .

ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 2010, 104 (04) :327-330

[4] Controlling the spread of carbapenemase-producing Gram-negatives: therapeutic approach and infection control [J].

Carmeli, Y. ;

Akova, M. ;

Cornaglia, G. ;

Daikos, G. L. ;

Garau, J. ;

Harbarth, S. ;

Rossolini, G. M. ;

Souli, M. ;

Giamarellou, H. .

CLINICAL MICROBIOLOGY AND INFECTION, 2010, 16 (02) :102-111

[5] Development of a set of multiplex PCR assays for the detection of genes encoding important β-lactamases in Enterobacteriaceae [J].

Dallenne, Caroline ;

Da Costa, Anaelle ;

Decre, Dominique ;

Favier, Christine ;

Arlet, Guillaume .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2010, 65 (03) :490-495

[6] An Ertapenem-Resistant Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae Clone Carries a Novel OmpK36 Porin Variant [J].

Garcia-Fernandez, Aurora ;

Miriagou, Vivi ;

Papagiannitsis, Costas C. ;

Giordano, Alessandra ;

Venditti, Mario ;

Mancini, Carlo ;

Carattoli, Alessandra .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2010, 54 (10) :4178-4184

[7] Plasmid-encoded OXA-48 carbapenemase in Escherichia coli from Israel [J].

Goren, Moran G. ;

Chmelnitsky, Inna ;

Carmeli, Yehuda ;

Navon-Venezia, Shiri .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (03) :672-673

[8] Role of β-lactamases and porins in resistance to ertapenem and other β-lactams in Klebsiella pneumoniae [J].

Jacoby, GA ;

Mills, DM ;

Chow, N .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (08) :3203-3206

[9] High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of blaACT-1 β-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin PhoE [J].

Kaczmarek, Frank M. ;

Dib-Hajj, Fadia ;

Shang, Wenchi ;

Gootz, Thomas D. .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (10) :3396-3406

[10] Spread of Klebsiella pneumoniae isolates producing OXA-48 β-lactamase in a Tunisian university hospital [J].

Ktari, Sonia ;

Mnif, Basma ;

Louati, Fadoua ;

Rekik, Sonia ;

Mezghani, Sonda ;

Mahjoubi, Fouzia ;

Hammami, Adnane .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (07) :1644-1646

← 1 2 →