Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney: long-term results

被引:14
作者
Krokidis, Miltiadis [1 ]
Spiliopoulos, Stavros [1 ]
Jarzabek, Magdalena [1 ]
Fotiadis, Nikos [2 ]
Sabharwal, Tarun [1 ]
O'Brien, Tim [3 ]
Adam, Andy [1 ]
机构
[1] Guys & St Thomas Hosp NHS Fdn Trust, Dept Radiol, London SE1 7EH, England
[2] Royal Marsden NHS Fdn Trust, Dept Radiol, London, England
[3] Guys & St Thomas Hosp NHS Fdn Trust, Dept Urol, London SE1 7EH, England
关键词
Renal cancer; Nephrons; Radiofrequency catheter ablation; Ablation techniques; Nephrectomy; ETHANOL INJECTION; CRYOABLATION; FEATURES; OUTCOMES; MASSES; VIVO;
D O I
10.1007/s00330-013-2802-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
To evaluate the long-term results of percutaneous radiofrequency ablation (RFA) of small renal tumours in patients with a single functioning kidney (SFK). This is a single-centre prospective study. Patients with an SFK and a tumour smaller than 3.5 cm, treated with RFA over a 7.5-year period, were included. Nineteen consecutive patients (12 male), aged between 33 and 83 years (mean 61.4), were treated for 23 lesions. Primary endpoints were technical success and tumour recurrence rate. Secondary endpoints were the deterioration of renal function and overall survival rate. The mean follow-up was 56.1 months (range 36-102). Primary technical success was 100 %. There were no major peri-procedural complications. In two cases, minor complications occurred. There was no significant difference between the baseline glomerular filtration rate (GFR) and GFR at 3, 12 and 24 months post-procedure. In four lesions (17 %), recurrence was detected and an additional RFA session was performed. None of the patients developed renal failure during their lifetime. Three of the patients died because of other reasons. Percutaneous RFA of small renal tumours in patients with an SFK offers very satisfactory long-term results regarding preservation of renal function, local tumour control and overall survival. aEuro cent Tumour in a single functioning kidney requires minimally invasive treatment. aEuro cent Radiofrequency ablation plays an established role in managing small renal tumours. aEuro cent Long-term results of radiofrequency ablation have shown satisfactory local tumour control. aEuro cent Long-term results have also shown that renal function may be preserved.
引用
收藏
页码:1933 / 1939
页数:7
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