COX-2 and cancer: a new approach to an old problem

被引:106
|
作者
Bakhle, YS [1 ]
机构
[1] Univ London Imperial Coll Sci & Technol, Fac Med, Div Biomed Sci, London SW7 2AZ, England
关键词
angiogenesis; APC; apoptosis; aspirin; breast; (cancer); carcinogenesis; chemoprevention; chemotherapy; colorectal; (cyclo-oxygenase); cytokines; epidemiology; FAP; HNPCC; lung; Min mouse; NSAID; PPAR; prostate; sulindac; thiazolidinedione;
D O I
10.1038/sj.bjp.0704365
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
[No abstract available]
引用
收藏
页码:1137 / 1150
页数:14
相关论文
共 50 条
  • [1] COX-2 inhibition and prevention of cancer
    Giercksky, KE
    BEST PRACTICE & RESEARCH CLINICAL GASTROENTEROLOGY, 2001, 15 (05) : 821 - 833
  • [2] COX-2 as a target for cancer chemotherapy
    Ghosh, Nilanjan
    Chaki, Rituparna
    Mandal, Vivekananda
    Mandal, Subhash C.
    PHARMACOLOGICAL REPORTS, 2010, 62 (02) : 233 - 244
  • [3] COX-2 as a target for cancer chemotherapy
    Nilanjan Ghosh
    Rituparna Chaki
    Vivekananda Mandal
    Subhash C. Mandal
    Pharmacological Reports, 2010, 62 : 233 - 244
  • [4] COX-2 Signaling and Cancer: New Players in Old Arena
    Misra, Shashank
    Sharma, Kulbhushan
    CURRENT DRUG TARGETS, 2014, 15 (03) : 347 - 359
  • [5] Biology of Cox-2: An Application in Cancer Therapeutics
    Khan, Zakir
    Khan, Noor
    Tiwari, Ram P.
    Sah, Nand K.
    Prasad, G. B. K. S.
    Bisen, Prakash S.
    CURRENT DRUG TARGETS, 2011, 12 (07) : 1082 - 1093
  • [6] Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
    B. Agarwal
    P. Swaroop
    P. Protiva
    S. V. Raj
    H. Shirin
    P. R. Holt
    Apoptosis, 2003, 8 : 649 - 654
  • [7] Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
    Agarwal, B
    Swaroop, P
    Protiva, P
    Raj, SV
    Shirin, H
    Holt, PR
    APOPTOSIS, 2003, 8 (06) : 649 - 654
  • [8] Cancer and cyclooxygenase-2 (COX-2) inhibition
    Evans, JF
    Kargman, SL
    CURRENT PHARMACEUTICAL DESIGN, 2004, 10 (06) : 627 - 634
  • [9] COX-2 Inhibitors and Gastric Cancer
    Wang, Zhen
    Chen, Jun-qiang
    Liu, Jin-lu
    GASTROENTEROLOGY RESEARCH AND PRACTICE, 2014, 2014
  • [10] Mechanisms of colon cancer prevention with and beyond COX-2 inhibition
    Rodríguez-Moranta, F
    Castells, A
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2005, 5 (05) : 505 - 516