Clinical outcomes of ultrathin strut biodegradable polymer-coated everolimus-eluting stent in patients with coronary artery disease

被引:4
作者
Patted, Suresh, V [1 ]
Thakkar, Ashok S. [2 ]
机构
[1] KLE Acad Higher Educ & Res, Dept Cardiol, Belagavi, Karnataka, India
[2] Meril Life Sci Pvt Ltd, Dept Clin Res, Vapi, Gujarat, India
关键词
Coronary Artery Disease; Drug-Eluting Stent; Everolimus; Percutaneous Coronary Intervention; NON-INFERIORITY; INTERVENTION; MULTICENTER; RESTENOSIS; GUIDELINE; EFFICACY; SAFETY;
D O I
10.22122/arya.v16i3.1827
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: Evermine 50 (TM) (Meril Life Sciences Pvt. Ltd., India) everolimus-eluting stent system (EES) is a novel ultrathin strut (50 mu m) cobalt-chromium coronary drug-eluting stent (DES) platform with biodegradable polymer coating. The Evermine 50 EES-KLES study aimed to evaluate the Evermine 50 EES in terms of 24-month clinical safety and performance in patients with coronary artery disease (CAD). METHODS: This retrospective study consisted of 171 patients (258 lesions) implanted with Evermine 50 EES for managing CAD. We analyzed the major adverse cardiac events (MACE) incidence, defined as a composite of cardiac death, myocardial infarction, and ischemia-driven target lesion revascularization (ID-TLR) at 6-, 12-, and 24-month follow-up. RESULTS: A total of 171 patients were included with a mean age of 57.85 +/- 10.05 years, of which, 139 (81.29%) were men, 69 (40.35%) were hypertensive, and 70 (40.94%) were diabetic. The incidence of MACE was 1(0.58%), 3 (1.81%), and 4 (2.42%) at 6-, 12-, and 24-month follow-up, respectively. There were three cases (1.82%) of cardiac death and one case (0.61%) of ID-TLR up to 24 months. None of the patients was presented with definite or probable stent thrombosis (ST). CONCLUSION: This study demonstrated that implantation of ultrathin strut Evermine 50 EES resulted in a low rate of incidence of MACE, indicating a favourable clinical safety and performance profile of Evermine 50 EES in patients with CAD.
引用
收藏
页码:130 / 135
页数:6
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