Correlation Analysis of Erectile Dysfunction with Lower Urinary Tract Symptoms (LUTS) Degree and Clinical Features in LUTS Patients

Background: We aimed to investigate the prevalence of erectile dysfunction (ED) in patients with lower urinary tract symptoms (LUTS) and to explore the correlation of ED with LUTS and its clinical features. Methods: Overall, 400 outpatients and inpatients with LUTS diagnosed in Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, Henan Province, China from June 2015 to June 2017 were collected. LUTS degree was assessed by the International Prostate Symptom Score (IPSS), and ED degree was assessed by the International Index of Erectile Function (IIEF-5). The correlation of ED with LUTS degree, age, blood lipids, homocysteine (Hcy) and other factors was analyzed. Results: The prevalence of ED in patients with LUTS was 82.25%. With the increase in age, the prevalence of ED was significantly elevated, and ED degree gradually became higher (P<0.01). The higher the degree of LUTS was, the higher the prevalence of ED would be. The degree of ED was highly correlated with the combination with hypertension, diabetes mellitus and coronary heart disease (P<0.05). The prevalence of ED was positively correlated with LUTS degree and the levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and Hcy (P<0.05 or P<0.01). Conclusion: ED prevalence of patients with LUTS is high, and ED is significantly related to LUTS degree, age and the levels of TC, LDL-C and Hcy in patients with LUTS.