Backbone and side-chain 1H, 15N, 13C assignment and secondary structure of BPSL1445 from Burkholderia pseudomallei

被引:1
作者
Quilici, Giacomo [1 ]
Berardi, Andrea [1 ]
Gaudesi, Davide [1 ]
Gourlay, Louise J. [2 ]
Bolognesi, Martino [2 ]
Musco, Giovanna [1 ]
机构
[1] S Raffaele Sci Inst, Biomol NMR Unit, Milan, Italy
[2] Univ Milan, Dept Biosci, I-20133 Milan, Italy
关键词
Melioidosis; Infectious diseases; Host-pathogen interactions; Vaccine; Biological warfare agent; MELIOIDOSIS; SPECTROSCOPY; VACCINES;
D O I
10.1007/s12104-015-9607-1
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
BPSL1445 is a lipoprotein produced by the Gram-negative bacterium Burkholderia pseudomallei (B. pseudomallei), the etiological agent of melioidosis. Immunodetection assays against sera patients using protein microarray suggest BPSL1445 involvement in melioidosis. Herein we report backbone, side chain NMR assignment and secondary structure for the recombinant protein.
引用
收藏
页码:347 / 350
页数:4
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