Magnetic Compression of Polyelectrolyte Microcapsules for Controlled Release

被引：11

作者：

Hu, Yanan ^{[1
]}

Liu, Chuanyong ^{[3
,4
]}

Li, Dongzhi ^{[3
,4
]}

Long, Yue ^{[1
]}

Song, Kai ^{[1
]}

Tung, Chen-Ho ^{[2
]}

机构：

[1] Chinese Acad Sci, Lab Bioinspired Smart Interface Sci, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Key Lab Photochem Convers & Optoelect Mat, Tech Inst Phys & Chem, Beijing 100190, Peoples R China

[3] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China

[4] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

LANGMUIR | 2015年 / 31卷 / 41期

基金：

中国国家自然科学基金;

关键词：

DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; MULTILAYER CAPSULES; CELL ENCAPSULATION; MICROENCAPSULATION; NANOPARTICLES; PERMEABILITY; ROUTE; SIZE;

D O I：

10.1021/acs.langmuir.5b02229

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, microcapsules with a magnetic particle as the core and polyelectrolyte multilayers as the shell were fabricated. The cavity of the microcapsules was created by etching the SiO2 layer, which was first coated on the magnetic core particle, and the size of the cavity can be adjusted by the thickness of the SiO2 layer. This magnetically responsive microcapsule deforms upon application of a constant magnetic field and results in the release of the core content, and the release velocity could be controlled by the strength of the magnetic field. This release mechanism is proactive and repeatable, combined with its localized and remote controllability; it can be a powerful tool for delivering medical agents on site.

引用

页码：11195 / 11199

页数：5

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