Magnetic Compression of Polyelectrolyte Microcapsules for Controlled Release

被引:11
作者
Hu, Yanan [1 ]
Liu, Chuanyong [3 ,4 ]
Li, Dongzhi [3 ,4 ]
Long, Yue [1 ]
Song, Kai [1 ]
Tung, Chen-Ho [2 ]
机构
[1] Chinese Acad Sci, Lab Bioinspired Smart Interface Sci, Beijing 100190, Peoples R China
[2] Chinese Acad Sci, Key Lab Photochem Convers & Optoelect Mat, Tech Inst Phys & Chem, Beijing 100190, Peoples R China
[3] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China
[4] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
基金
中国国家自然科学基金;
关键词
DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; MULTILAYER CAPSULES; CELL ENCAPSULATION; MICROENCAPSULATION; NANOPARTICLES; PERMEABILITY; ROUTE; SIZE;
D O I
10.1021/acs.langmuir.5b02229
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this study, microcapsules with a magnetic particle as the core and polyelectrolyte multilayers as the shell were fabricated. The cavity of the microcapsules was created by etching the SiO2 layer, which was first coated on the magnetic core particle, and the size of the cavity can be adjusted by the thickness of the SiO2 layer. This magnetically responsive microcapsule deforms upon application of a constant magnetic field and results in the release of the core content, and the release velocity could be controlled by the strength of the magnetic field. This release mechanism is proactive and repeatable, combined with its localized and remote controllability; it can be a powerful tool for delivering medical agents on site.
引用
收藏
页码:11195 / 11199
页数:5
相关论文
共 50 条
  • [21] Controlled release of vancomycin from biodegradable microcapsules
    Özalp, Y
    Özdemir, N
    Kocagöz, S
    Hasirci, V
    JOURNAL OF MICROENCAPSULATION, 2001, 18 (01) : 89 - 110
  • [22] Synthesis of Nonspherical Microcapsules through Controlled Polyelectrolyte Coating of Hydrogel Templates
    Chen, Lynna
    An, Harry Z.
    Doyle, Patrick S.
    LANGMUIR, 2015, 31 (33) : 9228 - 9235
  • [23] Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells
    Vergaro, Viviana
    Scarlino, Flavia
    Bellomo, Claudia
    Rinaldi, Rosaria
    Vergara, Daniele
    Maffia, Michele
    Baldassarre, Francesca
    Giannelli, Gianluigi
    Zhang, Xingcai
    Lvov, Yuri M.
    Leporatti, Stefano
    ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (09) : 847 - 863
  • [24] Intracellularly Biodegradable Polyelectrolyte/Silica Composite Microcapsules as Carriers for Small Molecules
    Gao, Hui
    Goryacheva, Olga A.
    Tarakina, Nadezda V.
    Sukhorukov, Gleb B.
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (15) : 9651 - 9661
  • [25] Magnetic polyelectrolyte microcapsules via water-in-water droplet microfluidics
    Navi, Maryam
    Kieda, Jennifer
    Tsai, Scott S. H.
    LAB ON A CHIP, 2020, 20 (16) : 2851 - 2860
  • [26] Temperature controlled loading and release of curcumin in polyelectrolyte multilayers thin films
    Saikaew, Rateeya
    Marsal, Philippe
    Grenier, Benjamin
    Dubas, Stephan Thierry
    MATERIALS LETTERS, 2018, 215 : 38 - 41
  • [27] Chitosan-TPP microcapsules for controlled drug release
    Perez-Pacheco, Yaride
    Alimandi, Tiziano
    Tylkowski, Bartosz
    Sistere, Miquel
    Garcia-Valls, Ricard
    AFINIDAD, 2024, 81 (601) : 33 - 42
  • [28] Controlled Release of Phosphate Fertilizer Using Silica Microcapsules
    Fujiwara, Masahiro
    Shoji, Shigeru
    Murakami, Yuka
    CHEMISTRY LETTERS, 2019, 48 (07) : 658 - 661
  • [29] Preparation of uniform starch microcapsules by premix membrane emulsion for controlled release of avermectin
    Li, Dan
    Liu, Baoxia
    Yang, Fei
    Wang, Xing
    Shen, Hong
    Wu, Decheng
    CARBOHYDRATE POLYMERS, 2016, 136 : 341 - 349
  • [30] Characterization of Polymeric Microcapsules Containing a Low Molecular Weight Peptide for Controlled Release
    Moore, Keith
    Amos, Jennifer
    Davis, Jeffrey
    Gourdie, Robert
    Potts, Jay D.
    MICROSCOPY AND MICROANALYSIS, 2013, 19 (01) : 213 - 226