Factor analyses of metabolic syndrome: A systematic review with special reference to Asian Indians

Background: Metabolic syndrome is the constellation of cardiovascular disease risk factors and a growing public health issue affecting more than 20% of world population. Factor analysis is a powerful mathematical tool in exploring the underlying factors of any chronic diseases. Although it is most often criticized for its contrasting results for a common expression differently interpreted by the researchers yet fit the original data equally well. Objective: The present study aims to find out the underlying physiological domains for the phenotypic attribution of metabolic syndrome as documented in several studies. Methodology: Literature search was done using Google Scholar, PUBMED, Research Gate and manual searching to identify relevant studies of the selected topic. Conclusion: More than one physiological domain has been explored for the expression of metabolic syndrome explored in different studies. A reason for this disparity may be because most of explored factors are just mathematically significant but not biologically. Another reason may be the varied factor load concern. Therefore, a fixed factor load value is needed to be restricted for all studies across world. (C) 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.