Guidelines Updates in the Treatment of Obesity or Metabolic Syndrome and Hypertension

被引:29
作者
Cerezo, Cesar [1 ]
Segura, Julian [1 ]
Praga, Manuel [1 ]
Ruilope, Luis M. [1 ,2 ]
机构
[1] Hosp 12 Octubre, Dept Nephrol, Hypertens Unit, E-28041 Madrid, Spain
[2] Univ Autonoma Madrid, Dept Publ Hlth & Prevent Med, Madrid, Spain
关键词
Obesity; Abdominal obesity; Overweight; Metabolic syndrome; Diabetes; Blood pressure; Dyslipidemia; Risk factors; Cardiovascular disease; Body mass index; BMI; Body fat distribution; Lifestyle changes; Bariatric surgery; Hypertension; Obesity paradox; Guidelines; CORONARY-HEART-DISEASE; BODY-MASS INDEX; ALL-CAUSE MORTALITY; RISK; FAT; WEIGHT; OVERWEIGHT; AMLODIPINE; ADIPOSITY; ADULTS;
D O I
10.1007/s11906-013-0337-4
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Obesity and overweight are nowadays very prevalent worldwide. They are known to be linked with an increased risk of developing cardiovascular comorbidities and mortality. Abdominal obesity is frequently associated with a collection of metabolic disorders that include elevated blood pressure, characteristic lipid abnormalities (low high-density lipoprotein cholesterol and high triglycerides) and increased fasting glucose, with an underlying situation of insulin resistance, which has been defined as metabolic syndrome, conferring a high cardiovascular risk profile to these subjects. A multidisciplinary approach is required, including lifestyle changes and pharmacological and surgical approaches. Intensive management of all the risk factors of the metabolic syndrome is also needed to reduce body weight and waist circumference, lessen insulin resistance and avoid the development of new-onset diabetes and cardiovascular disease associated with this entity. This article will review the recently published literature and guideline updates on this topic, although it is not yet included in the highlights.
引用
收藏
页码:196 / 203
页数:8
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