Mobile gene cassettes and integrons in evolution

被引:116
作者
Hall, RM
Collis, CM
Kim, MJ
Partridge, SR
Recchia, GD
Stokes, HW
机构
[1] CSIRO, Sydney Lab, N Ryde, NSW 1670, Australia
[2] Macquarie Univ, Sch Biol Sci, Sydney, NSW 2109, Australia
来源
MOLECULAR STRATEGIES IN BIOLOGICAL EVOLUTION | 1999年 / 870卷
关键词
D O I
10.1111/j.1749-6632.1999.tb08866.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Integrons and the site-specific recombination systems encoded by them provide a simple mechanism for the addition of new genes to bacterial chromosomes. Although there is substantial divergence among the four known integron encoded integrases, they all recognize the recombination sites, known as 59-base elements, that are associated with genes that are packaged in gene cassettes. In contrast, the integron-associated recombination sites, attI sites, are preferentially recognized by the cognate integrase.
引用
收藏
页码:68 / 80
页数:13
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