Backbone 1H, 13C, and 15N resonance assignments of guanylyl cyclase activating protein-1, GCAP1

被引:3
作者
Lim, Sunghyuk [1 ]
Peshenko, Igor V. [2 ]
Dizhoor, Alexander M. [2 ]
Ames, James B. [1 ]
机构
[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA
[2] Salus Univ, Penn Coll Optometry, Elkins Pk, PA 19027 USA
关键词
GCAP1; Phototransduction; Calcium; EF-hand; Guanylate cyclase; NMR; NEURONAL CALCIUM SENSOR; ZEBRAFISH; DIVERSITY; CLONING; CA2+;
D O I
10.1007/s12104-012-9373-2
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Guanylyl cyclase activating protein 1 (GCAP1), a member of the neuronal calcium sensor subclass of the calmodulin superfamily, confers Ca2+-dependent activation of retinal guanylyl cyclase that regulates the visual light response. GCAP1 is genetically linked to retinal degenerative diseases. We report backbone NMR chemical shift assignments of Ca2+-saturated GCAP1 (BMRB no. 18026).
引用
收藏
页码:39 / 42
页数:4
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