Determination of uric acid in the presence of ascorbic acid using poly(3,4-ethylenedioxythiophene)-modified electrodes

被引：59
作者：
Kumar, SS
Mathiyarasu, J [1 ]
Phani, KL
Jain, YK
Yegnaraman, V
机构：
[1] Cent Electrochem Res Inst, Electrod & Electrocatalysis Div, Karaikkudi 630006, Tamil Nadu, India
[2] Cent Elect Engn Res Inst, MEMS Packaging Grp, Pilani 333031, Rajasthan, India
来源：
ELECTROANALYSIS | 2005年 / 17卷 / 24期
关键词：
conducting polymer; poly(3,4-ethylenedioxythiophene); uric acid; ascorbic acid; voltammetry;
D O I：
10.1002/elan.200503375
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A poly(3,4-ethylenedioxythiophene) (PEDOT) modified glassy carbon electrode (GCE) was used to determine uric acid in the presence of ascorbic acid at physiological pH facilitating a peak potential separation of ascorbic acid and uric acid oxidation (ca. 365 mV), which is the largest value reported so far in the literature. Also, an analytical protocol involving differential pulse voltammetry has been developed using a microchip electrode for the determination of uric acid in the concentration range of to 20 mu M in presence of excess of ascorbic acid.
引用
收藏
页码：2281 / 2286
页数：6
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