DRUG THERAPY Management of Opioid Analgesic Overdose

被引:369
作者
Boyer, Edward W. [1 ]
机构
[1] Univ Massachusetts, Med Ctr, Dept Emergency Med, Div Med Toxicol, Worcester, MA 01655 USA
关键词
INTRAVENOUS NALOXONE; PULMONARY-EDEMA; UNITED-STATES; SEPTIC SHOCK; CHILDREN; MORPHINE; DEATHS; DISPOSITION; METHADONE; PHARMACOKINETICS;
D O I
10.1056/NEJMra1202561
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Opioid analgesic overdose is a life-threatening condition, and the antidote naloxone may have limited effectiveness in patients with poisoning from long-acting agents. The unpredictable clinical course of intoxication demands empirical management of this potentially lethal condition. Copyright © 2012 Massachusetts Medical Society.
引用
收藏
页码:146 / 155
页数:10
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