Rosette-forming glioneuronal tumor - evidence of stem cell origin with biphenotypic differentiation

被引：16

作者：

Chakraborti, S. ^{[2
]}

Mahadevan, A. ^{[1
]}

Govindan, A. ^{[3
]}

Bhateja, A. ^{[4
]}

Dwarakanath, S. ^{[5
]}

Aravinda, H. R. ^{[6
]}

Phalguni, A. A. ^{[7
]}

Santosh, V. ^{[1
]}

Yasha, T. C. ^{[1
]}

Rout, P. ^{[8
]}

Sampath, S. ^{[5
]}

Shankar, S. K. ^{[1
]}

机构：

[1] Natl Inst Mental Hlth & Neurosci, Dept Neuropathol, Bangalore 560029, Karnataka, India

[2] Kasturba Med Coll & Hosp, Dept Pathol, Mangalore, Karnataka, India

[3] Govt Med Coll, Dept Pathol, Kozhikode, Kerala, India

[4] Sita Bhateja Hospial, Bangalore, Karnataka, India

[5] Natl Inst Mental Hlth & Neurosci, Dept Neurosurg, Bangalore 560029, Karnataka, India

[6] Natl Inst Mental Hlth & Neurosci, Dept Neuroimaging & Intervent Radiol, Bangalore 560029, Karnataka, India

[7] Natl Inst Mental Hlth & Neurosci, Dept Neurophysiol, Bangalore 560029, Karnataka, India

[8] St Johns Med Coll & Hosp, Dept Pathol, Bangalore, Karnataka, India

来源：

VIRCHOWS ARCHIV | 2012年 / 461卷 / 05期

关键词：

Glioneuronal tumor; Rosette-forming glioneuronal tumor; GFAP; Synaptophysin; CD133; Stem cell; Confocal microscopy; NERVOUS-SYSTEM TUMORS; 4TH-VENTRICLE REPORT;

D O I：

10.1007/s00428-012-1313-0

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle is a new addition to the WHO classification of central nervous system tumors. To date, 72 cases have been described in literature. In the present study, we report the clinical and imaging features, with detailed histopathological and immunohistochemical profile, of eight cases. Confocal microscopic evidence of stem cell origin with biphenotypic, glial and neurocytic differentiation is presented with a comprehensive review of literature.

引用

页码：581 / 588

页数：8

共 45 条

[1] Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case report [J].

Adachi, J ;

Nishikawa, R ;

Hirose, T ;

Matsutani, M .

SURGICAL NEUROLOGY, 2005, 63 (04) :375-379

[2] Rosette-forming glioneuronal tumour of the fourth ventricle: report of a case with clinical and surgical implications [J].

Albanese, A ;

Mangiola, A ;

Pompucci, A ;

Sabatino, G ;

Gessi, M ;

Lauriola, L ;

Anile, C .

JOURNAL OF NEURO-ONCOLOGY, 2005, 71 (02) :195-197

[3] Rosette-Forming Glioneuronal Tumour of the 4th Ventricle in a NF1 Patient [J].

Alturkustani, Murad ;

Ang, Lee-Cyn .

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2012, 39 (01) :95-96

[4] Recently established entities of central nervous system tumors: Review of radiological findings [J].

Amemiya, Shiori ;

Shibahara, Junji ;

Aoki, Shigeki ;

Takao, Hidemasa ;

Ohtomo, Kuni .

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2008, 32 (02) :279-285

[5] A rosette-forming glioneuronal tumor of the spinal cord: the first case of a rosette-forming glioneuronal tumor originating from the spinal cord [J].

Anan, Mitsuhiro ;

Inoue, Ryo ;

Ishii, Keisuke ;

Abe, Tatsuya ;

Fujiki, Minoru ;

Kobayashi, Hidenori ;

Goya, Tomokazu ;

Nakazato, Yoichi .

HUMAN PATHOLOGY, 2009, 40 (06) :898-901

[6] Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle-Case Report [J].

Arai, Atsushi ;

Sasayama, Takashi ;

Tamaki, Masahiro ;

Sakagami, Yoshio ;

Enoki, Eisuke ;

Ohbayashi, Chiho ;

Kohmura, Eiji .

NEUROLOGIA MEDICO-CHIRURGICA, 2010, 50 (03) :224-228

[7] Current Strategies for Identification of Glioma Stem Cells: Adequate or Unsatisfactory? [J].

Brescia, Paola ;

Richichi, Cristina ;

Pelicci, Giuliana .

JOURNAL OF ONCOLOGY, 2012, 2012

[8]

Edgar MA, 2007, ARCH PATHOL LAB MED, V131, P228

[9] Recurrent PIK3CA mutations in rosette-forming glioneuronal tumor [J].

Ellezam, Benjamin ;

Theeler, Brett J. ;

Luthra, Rajyalakshmi ;

Adesina, Adekunle M. ;

Aldape, Kenneth D. ;

Gilbert, Mark R. .

ACTA NEUROPATHOLOGICA, 2012, 123 (02) :285-287

[10] A rosette-forming glioneuronal tumour of the pineal gland [J].

Frydenberg, E. ;

Laherty, R. ;

Rodriguez, M. ;

Ow-Yang, M. ;

Steel, T. .

JOURNAL OF CLINICAL NEUROSCIENCE, 2010, 17 (10) :1326-1328

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